"DNA Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
- DNA Probes
- Probes, DNA
- DNA Hybridization Probes
- Hybridization Probes, DNA
- Probes, DNA Hybridization
Below are MeSH descriptors whose meaning is more general than "DNA Probes".
Below are MeSH descriptors whose meaning is more specific than "DNA Probes".
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Below are the most recent publications written about "DNA Probes" by people in Profiles.
DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy. BMC Biol. 2020 03 24; 18(1):32.
RNA fluorescence in situ hybridization in cultured mammalian cells. Methods Mol Biol. 2015; 1206:123-36.
Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes. Acc Chem Res. 2011 Sep 20; 44(9):709-17.
Profiling non-lysyl tRNAs in HIV-1. RNA. 2010 Feb; 16(2):267-73.
A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT). J Am Chem Soc. 2008 Dec 31; 130(52):17634-5.
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia. Blood. 2008 Nov 15; 112(10):4193-201.
Diazirine-based DNA photo-cross-linking probes for the study of protein-DNA interactions. Angew Chem Int Ed Engl. 2008; 47(1):90-3.
Exon-based mapping of microarray probes: recovering differential gene expression signal in underpowered hypoxia experiment. Mol Cell Probes. 2007 Apr; 21(2):134-9.
A statistical framework for genome-wide discovery of biomarker splice variations with GeneChip Human Exon 1.0 ST Arrays. Genome Inform. 2006; 17(1):88-99.
Low-grade B-Cell lymphomas with plasmacytic differentiation lack PAX5 gene rearrangements. J Mol Diagn. 2005 Aug; 7(3):346-51.