"DNA Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
| Descriptor ID |
D015342
|
| MeSH Number(s) |
D13.444.600.223 D27.505.259.750.600.223 D27.720.470.530.600.223
|
| Concept/Terms |
DNA Probes- DNA Probes
- Probes, DNA
- DNA Hybridization Probes
- Hybridization Probes, DNA
- Probes, DNA Hybridization
|
Below are MeSH descriptors whose meaning is more general than "DNA Probes".
Below are MeSH descriptors whose meaning is more specific than "DNA Probes".
This graph shows the total number of publications written about "DNA Probes" by people in this website by year, and whether "DNA Probes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 3 | 3 |
| 1995 | 1 | 5 | 6 |
| 1996 | 0 | 2 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 3 | 0 | 3 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Probes" by people in Profiles.
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DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy. BMC Biol. 2020 03 24; 18(1):32.
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RNA fluorescence in situ hybridization in cultured mammalian cells. Methods Mol Biol. 2015; 1206:123-36.
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Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes. Acc Chem Res. 2011 Sep 20; 44(9):709-17.
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Profiling non-lysyl tRNAs in HIV-1. RNA. 2010 Feb; 16(2):267-73.
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A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT). J Am Chem Soc. 2008 Dec 31; 130(52):17634-5.
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An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia. Blood. 2008 Nov 15; 112(10):4193-201.
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Diazirine-based DNA photo-cross-linking probes for the study of protein-DNA interactions. Angew Chem Int Ed Engl. 2008; 47(1):90-3.
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Exon-based mapping of microarray probes: recovering differential gene expression signal in underpowered hypoxia experiment. Mol Cell Probes. 2007 Apr; 21(2):134-9.
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A statistical framework for genome-wide discovery of biomarker splice variations with GeneChip Human Exon 1.0 ST Arrays. Genome Inform. 2006; 17(1):88-99.
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Low-grade B-Cell lymphomas with plasmacytic differentiation lack PAX5 gene rearrangements. J Mol Diagn. 2005 Aug; 7(3):346-51.