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Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.
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Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.
Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease. Neuron. 2010 Sep 09; 67(5):769-80.
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PubMed
subject areas
Alzheimer Disease
Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Amyloid Precursor Protein Secretases
Analysis of Variance
Animals
Antibodies
Butyrates
Cadherins
Cells, Cultured
Cricetinae
Cricetulus
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Inhibitors
Enzyme-Linked Immunosorbent Assay
Female
Fluorescence Resonance Energy Transfer
Gene Expression Regulation
Humans
Hydrocarbons, Halogenated
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Peptide Fragments
Presenilin-1
Rats
Receptors, Notch
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Transfection
authors with profiles
Sangram S. Sisodia