"Cadherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.
| Descriptor ID |
D015820
|
| MeSH Number(s) |
D12.776.395.550.200.200 D12.776.543.550.200.200 D23.050.301.350.200
|
| Concept/Terms |
P-Cadherins- P-Cadherins
- P Cadherins
- P-Cadherin
- P Cadherin
- Placental Cadherins
- Cadherins, Placental
- Cadherin-3
- Cadherin 3
E-Cadherins- E-Cadherins
- E Cadherins
- Uvomorulin
- Epithelial-Cadherins
- Epithelial Cadherins
- Cadherin-1
- Cadherin 1
- E-Cadherin
- E Cadherin
N-Cadherins- N-Cadherins
- N Cadherins
- N-Cadherin
- N Cadherin
- Neural Cadherins
- Cadherins, Neural
- Cadherin-2
- Cadherin 2
|
Below are MeSH descriptors whose meaning is more general than "Cadherins".
Below are MeSH descriptors whose meaning is more specific than "Cadherins".
This graph shows the total number of publications written about "Cadherins" by people in this website by year, and whether "Cadherins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 1 | 3 |
| 2001 | 2 | 1 | 3 |
| 2002 | 3 | 1 | 4 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 2 | 3 |
| 2007 | 3 | 0 | 3 |
| 2008 | 5 | 2 | 7 |
| 2009 | 4 | 4 | 8 |
| 2010 | 3 | 5 | 8 |
| 2011 | 2 | 4 | 6 |
| 2012 | 5 | 1 | 6 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 4 | 7 |
| 2015 | 1 | 8 | 9 |
| 2016 | 5 | 8 | 13 |
| 2017 | 5 | 1 | 6 |
| 2018 | 0 | 4 | 4 |
| 2019 | 1 | 3 | 4 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 5 | 5 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 2 | 3 |
| 2025 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cadherins" by people in Profiles.
-
Advancing the Evaluation and Management of CDH1-Associated Gastric Cancer. J Natl Compr Canc Netw. 2025 04; 23(4).
-
Dachsous and Fat coordinately repress the Dachs-Dlish-Approximated complex to control growth. J Cell Biol. 2024 Dec 02; 223(12).
-
Germline CDH1 Variants and Lifetime Cancer Risk. JAMA. 2024 09 03; 332(9):722-729.
-
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18):e2319833121.
-
Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage. Int J Mol Sci. 2023 Nov 08; 24(22).
-
Fat2 polarizes Lar and Sema5c to coordinate the motility of collectively migrating epithelial cells. J Cell Sci. 2024 03 01; 137(5).
-
Epidermal stratification requires retromer-mediated desmoglein-1 recycling. Dev Cell. 2022 12 19; 57(24):2683-2698.e8.
-
Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration. Elife. 2022 09 26; 11.
-
Colorectal Neoplasia in CDH1 Pathogenic Variant Carriers: A Multicenter Analysis. Am J Gastroenterol. 2022 11 01; 117(11):1877-1879.
-
Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction. Curr Biol. 2022 05 09; 32(9):1986-2000.e5.