"Cadherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.
| Descriptor ID |
D015820
|
| MeSH Number(s) |
D12.776.395.550.200.200 D12.776.543.550.200.200 D23.050.301.350.200
|
| Concept/Terms |
P-Cadherins- P-Cadherins
- P Cadherins
- P-Cadherin
- P Cadherin
- Placental Cadherins
- Cadherins, Placental
- Cadherin-3
- Cadherin 3
E-Cadherins- E-Cadherins
- E Cadherins
- Uvomorulin
- Epithelial-Cadherins
- Epithelial Cadherins
- Cadherin-1
- Cadherin 1
- E-Cadherin
- E Cadherin
N-Cadherins- N-Cadherins
- N Cadherins
- N-Cadherin
- N Cadherin
- Neural Cadherins
- Cadherins, Neural
- Cadherin-2
- Cadherin 2
|
Below are MeSH descriptors whose meaning is more general than "Cadherins".
Below are MeSH descriptors whose meaning is more specific than "Cadherins".
This graph shows the total number of publications written about "Cadherins" by people in this website by year, and whether "Cadherins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 1 | 3 |
| 2001 | 2 | 1 | 3 |
| 2002 | 3 | 1 | 4 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 1 | 2 |
| 2006 | 3 | 2 | 5 |
| 2007 | 3 | 0 | 3 |
| 2008 | 6 | 2 | 8 |
| 2009 | 4 | 4 | 8 |
| 2010 | 3 | 5 | 8 |
| 2011 | 2 | 4 | 6 |
| 2012 | 5 | 1 | 6 |
| 2013 | 2 | 0 | 2 |
| 2014 | 4 | 4 | 8 |
| 2015 | 1 | 8 | 9 |
| 2016 | 5 | 8 | 13 |
| 2017 | 7 | 1 | 8 |
| 2018 | 2 | 4 | 6 |
| 2019 | 1 | 3 | 4 |
| 2020 | 3 | 2 | 5 |
| 2021 | 0 | 2 | 2 |
| 2022 | 2 | 5 | 7 |
| 2023 | 1 | 3 | 4 |
| 2024 | 1 | 3 | 4 |
| 2025 | 1 | 2 | 3 |
| 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cadherins" by people in Profiles.
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Initiation of rotational collective migration in Drosophila through tissue geometry and mechanochemical feedback. Proc Natl Acad Sci U S A. 2026 Aug 25; 123(34):e2528342123.
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Fat and Dachsous Signaling-Controlling Growth Requires Both Competition and Cooperation: Competitive Interactions at the Cell Cortex Restrict the Ability of an Unusual Protein Complex to Promote Tissue Growth. Bioessays. 2026 Jan; 48(1):e70103.
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Clinical decision tree for optimizing endoscopic assessment of signet ring cell carcinoma in hereditary diffuse gastric cancer surveillance. Endoscopy. 2025 10; 57(10):1118-1127.
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Structural basis for regulation of CELSR1 by a compact module in its extracellular region. Nat Commun. 2025 Apr 28; 16(1):3972.
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Advancing the Evaluation and Management of CDH1-Associated Gastric Cancer. J Natl Compr Canc Netw. 2025 04; 23(4).
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Dachsous and Fat coordinately repress the Dachs-Dlish-Approximated complex to control growth. J Cell Biol. 2024 12 02; 223(12).
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Germline CDH1 Variants and Lifetime Cancer Risk. JAMA. 2024 09 03; 332(9):722-729.
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Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proc Natl Acad Sci U S A. 2024 04 30; 121(18):e2319833121.
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CELSR1, a core planar cell polarity protein, features a weakly adhesive and flexible cadherin ectodomain. Structure. 2024 04 04; 32(4):476-491.e5.
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Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage. Int J Mol Sci. 2023 Nov 08; 24(22).