 Methylation
"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)
| Descriptor ID |
D008745
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| MeSH Number(s) |
G02.111.087.029.538 G02.149.115.029.538 G02.149.465.040.538 G02.607.750.040.538 G03.495.130.538
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methylation".
Below are MeSH descriptors whose meaning is more specific than "Methylation".
This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1983 | 0 | 1 | 1 | | 1984 | 0 | 2 | 2 | | 1985 | 1 | 2 | 3 | | 1987 | 0 | 2 | 2 | | 1988 | 0 | 2 | 2 | | 1989 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 2 | 2 | | 1992 | 0 | 3 | 3 | | 1993 | 0 | 4 | 4 | | 1995 | 0 | 2 | 2 | | 2001 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 5 | 5 | | 2006 | 0 | 6 | 6 | | 2007 | 3 | 5 | 8 | | 2008 | 0 | 3 | 3 | | 2009 | 0 | 3 | 3 | | 2010 | 0 | 14 | 14 | | 2011 | 0 | 10 | 10 | | 2012 | 0 | 10 | 10 | | 2013 | 0 | 12 | 12 | | 2014 | 0 | 8 | 8 | | 2015 | 0 | 14 | 14 | | 2016 | 1 | 15 | 16 | | 2017 | 0 | 11 | 11 | | 2018 | 0 | 16 | 16 | | 2019 | 1 | 9 | 10 | | 2020 | 0 | 8 | 8 | | 2021 | 0 | 7 | 7 |
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Below are the most recent publications written about "Methylation" by people in Profiles.
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Yang Z, Yang S, Cui YH, Wei J, Shah P, Park G, Cui X, He C, He YY. METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
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Richter WF, Shah RN, Ruthenburg AJ. Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia. Elife. 2021 07 15; 10.
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Wilamowski M, Sherrell DA, Minasov G, Kim Y, Shuvalova L, Lavens A, Chard R, Maltseva N, Jedrzejczak R, Rosas-Lemus M, Saint N, Foster IT, Michalska K, Satchell KJF, Joachimiak A. 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
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Wei J, He C. Chromatin and transcriptional regulation by reversible RNA methylation. Curr Opin Cell Biol. 2021 06; 70:109-115.
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Schachner LF, Jooß K, Morgan MA, Piunti A, Meiners MJ, Kafader JO, Lee AS, Iwanaszko M, Cheek MA, Burg JM, Howard SA, Keogh MC, Shilatifard A, Kelleher NL. Decoding the protein composition of whole nucleosomes with Nuc-MS. Nat Methods. 2021 03; 18(3):303-308.
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Want MY, Tsuji T, Singh PK, Thorne JL, Matsuzaki J, Karasik E, Gillard B, Cortes Gomez E, Koya RC, Lugade A, Odunsi K, Battaglia S. WHSC1/NSD2 regulates immune infiltration in prostate cancer. J Immunother Cancer. 2021 02; 9(2).
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Zhang LS, Liu C, He C. Transcriptome-Wide Detection of Internal N7-Methylguanosine. Methods Mol Biol. 2021; 2298:97-104.
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Du J, Liao W, Liu W, Deb DK, He L, Hsu PJ, Nguyen T, Zhang L, Bissonnette M, He C, Li YC. N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7.
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Sun HL, Zhu AC, Gao Y, Terajima H, Fei Q, Liu S, Zhang L, Zhang Z, Harada BT, He YY, Bissonnette MB, Hung MC, He C. Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 11 19; 80(4):633-647.e7.
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Li W, Zhou XJ. Methylation extends the reach of liquid biopsy in cancer detection. Nat Rev Clin Oncol. 2020 11; 17(11):655-656.
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