"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)
| Descriptor ID |
D008745
|
| MeSH Number(s) |
G02.111.035.538 G02.607.094.538 G03.059.538
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methylation".
Below are MeSH descriptors whose meaning is more specific than "Methylation".
This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 6 | 6 |
| 2006 | 0 | 6 | 6 |
| 2007 | 3 | 5 | 8 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 13 | 13 |
| 2011 | 0 | 10 | 10 |
| 2012 | 0 | 11 | 11 |
| 2013 | 0 | 12 | 12 |
| 2014 | 0 | 9 | 9 |
| 2015 | 0 | 16 | 16 |
| 2016 | 1 | 14 | 15 |
| 2017 | 0 | 11 | 11 |
| 2018 | 0 | 17 | 17 |
| 2019 | 1 | 10 | 11 |
| 2020 | 0 | 9 | 9 |
| 2021 | 0 | 7 | 7 |
| 2022 | 0 | 7 | 7 |
| 2023 | 0 | 10 | 10 |
| 2024 | 0 | 11 | 11 |
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Below are the most recent publications written about "Methylation" by people in Profiles.
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Central control of dynamic gene circuits governs T cell rest and activation. Nature. 2025 Jan; 637(8047):930-939.
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Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology. Nat Commun. 2024 Oct 18; 15(1):9008.
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m6A mRNA methylation by METTL14 regulates early pancreatic cell differentiation. EMBO J. 2024 Nov; 43(22):5445-5468.
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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1. Cell Metab. 2024 Oct 01; 36(10):2207-2227.e9.
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IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 Aug 28; 15(1):7421.
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Internal mRNA 2'-O-methyl mapping by nanopore sequencing and consequence on mRNA stability and role in cancer. Mol Cell. 2024 Jun 20; 84(12):2215-2217.
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Cell surface CD55 traffics to the nucleus leading to cisplatin resistance and stemness by inducing PRC2 and H3K27 trimethylation on chromatin in ovarian cancer. Mol Cancer. 2024 Jun 10; 23(1):121.
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m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024 05 18; 33(11):969-980.
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The YTHDF proteins display distinct cellular functions on m6A-modified RNA. Trends Biochem Sci. 2024 Jul; 49(7):611-621.
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Chemical manipulation of m1A mediates its detection in human tRNA. RNA. 2024 04 16; 30(5):548-559.