"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)
| Descriptor ID |
D008745
|
| MeSH Number(s) |
G02.111.035.538 G02.607.094.538 G03.059.538
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methylation".
Below are MeSH descriptors whose meaning is more specific than "Methylation".
This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 4 | 4 |
| 1995 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 5 | 5 |
| 2006 | 0 | 6 | 6 |
| 2007 | 3 | 5 | 8 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 13 | 13 |
| 2011 | 0 | 10 | 10 |
| 2012 | 0 | 10 | 10 |
| 2013 | 0 | 12 | 12 |
| 2014 | 0 | 8 | 8 |
| 2015 | 0 | 14 | 14 |
| 2016 | 1 | 14 | 15 |
| 2017 | 0 | 11 | 11 |
| 2018 | 0 | 16 | 16 |
| 2019 | 1 | 9 | 10 |
| 2020 | 0 | 8 | 8 |
| 2021 | 0 | 7 | 7 |
| 2022 | 0 | 6 | 6 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylation" by people in Profiles.
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Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial. Clin Cancer Res. 2023 02 16; 29(4):784-790.
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Epitranscriptome profiling of spleen mRNA m6A methylation reveals pathways of host responses to malaria parasite infection. Front Immunol. 2022; 13:998756.
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Detection of m6A RNA modifications at single-nucleotide resolution using m6A-selective allyl chemical labeling and sequencing. STAR Protoc. 2022 12 16; 3(4):101677.
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Deep learning modeling m6A deposition reveals the importance of downstream cis-element sequences. Nat Commun. 2022 05 17; 13(1):2720.
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The regulatory role of N6 -methyladenosine modification in the interaction between host and microbes. Wiley Interdiscip Rev RNA. 2022 Nov; 13(6):e1725.
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m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome. Nat Biotechnol. 2022 08; 40(8):1210-1219.
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The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590.
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METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
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Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia. Elife. 2021 07 15; 10.
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2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).