 Receptor-CD3 Complex, Antigen, T-Cell
"Receptor-CD3 Complex, Antigen, T-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Molecule composed of the non-covalent association of the T-cell antigen receptor (RECEPTORS, ANTIGEN, T-CELL) with the CD3 complex (ANTIGENS, CD3). This association is required for the surface expression and function of both components. The molecule consists of up to seven chains: either the alpha/beta or gamma/delta chains of the T-cell receptor, and four or five chains in the CD3 complex.
| Descriptor ID |
D017260
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| MeSH Number(s) |
D12.776.543.750.705.816.824.800 D23.050.301.264.035.103.800 D23.050.301.264.894.095.800 D23.101.100.110.103.800 D23.101.100.894.095.800
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| Concept/Terms |
Receptor-CD3 Complex, Antigen, T-Cell- Receptor-CD3 Complex, Antigen, T-Cell
- TCR-CD3 Complex
- Complex, TCR-CD3
- TCR CD3 Complex
- T-Cell Antigen Receptor-CD3 Complex
- T Cell Antigen Receptor CD3 Complex
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Below are MeSH descriptors whose meaning is more general than "Receptor-CD3 Complex, Antigen, T-Cell".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]
- Receptor-CD3 Complex, Antigen, T-Cell [D12.776.543.750.705.816.824.800]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, CD [D23.050.301.264.035]
- Antigens, CD3 [D23.050.301.264.035.103]
- Receptor-CD3 Complex, Antigen, T-Cell [D23.050.301.264.035.103.800]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- Antigens, CD3 [D23.050.301.264.894.095]
- Receptor-CD3 Complex, Antigen, T-Cell [D23.050.301.264.894.095.800]
- Biological Markers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, CD [D23.101.100.110]
- Antigens, CD3 [D23.101.100.110.103]
- Receptor-CD3 Complex, Antigen, T-Cell [D23.101.100.110.103.800]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- Antigens, CD3 [D23.101.100.894.095]
- Receptor-CD3 Complex, Antigen, T-Cell [D23.101.100.894.095.800]
Below are MeSH descriptors whose meaning is more specific than "Receptor-CD3 Complex, Antigen, T-Cell".
This graph shows the total number of publications written about "Receptor-CD3 Complex, Antigen, T-Cell" by people in this website by year, and whether "Receptor-CD3 Complex, Antigen, T-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptor-CD3 Complex, Antigen, T-Cell" by people in Profiles.
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Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WWA. The CD3 conformational change in the ?d T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing. Cell Rep. 2014 Jun 12; 7(5):1704-1715.
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Zullo AJ, Benlagha K, Bendelac A, Taparowsky EJ. Sensitivity of NK1.1-negative NKT cells to transgenic BATF defines a role for activator protein-1 in the expansion and maturation of immature NKT cells in the thymus. J Immunol. 2007 Jan 01; 178(1):58-66.
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Tang Q, Subudhi SK, Henriksen KJ, Long CG, Vives F, Bluestone JA. The Src family kinase Fyn mediates signals induced by TCR antagonists. J Immunol. 2002 May 01; 168(9):4480-7.
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Smith DM, Bluestone JA, Thistlethwaite JR, Woodle ES. Inhibition of T-cell activation by an anti-human class I MHC reactive monoclonal antibody occurs at a point distal to TCR-CD3 mediated signal transduction. Transplant Proc. 1995 Feb; 27(1):395-7.
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Mandal M, Beaman KD. Purification and characterization of a pregnancy-associated protein: TJ6s. Am J Reprod Immunol. 1995 Jan; 33(1):60-7.
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