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Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.
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Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.
Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells. Mol Cell. 2021 09 16; 81(18):3833-3847.e11.
View in:
PubMed
subject areas
Acetylation
Acetyl-CoA C-Acetyltransferase
Animals
Antineoplastic Agents
Female
Humans
Isocitrate Dehydrogenase
Ketoglutaric Acids
Leukemia, Myeloid, Acute
Lysine
Male
Mice
Mice, Inbred NOD
Mutation
NADP
Nuclear Proteins
Phosphorylation
Polymorphism, Single Nucleotide
Primary Cell Culture
Protein Binding
Protein Processing, Post-Translational
Protein-Tyrosine Kinases
authors with profiles
Jing Chen
Wendy Stock
Olatoyosi Odenike