"Ketoglutaric Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
| Descriptor ID |
D007656
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| MeSH Number(s) |
D02.241.081.337.351.502 D02.241.755.465
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ketoglutaric Acids".
Below are MeSH descriptors whose meaning is more specific than "Ketoglutaric Acids".
This graph shows the total number of publications written about "Ketoglutaric Acids" by people in this website by year, and whether "Ketoglutaric Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ketoglutaric Acids" by people in Profiles.
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Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells. Mol Cell. 2021 09 16; 81(18):3833-3847.e11.
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Role of Isocitrate Dehydrogenase 2 on DNA Hydroxymethylation in Human Airway Smooth Muscle Cells. Am J Respir Cell Mol Biol. 2020 07; 63(1):36-45.
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Metabolites, genome organization, and cellular differentiation gene programs. Curr Opin Immunol. 2018 04; 51:62-67.
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CCCTC-Binding Factor Translates Interleukin 2- and a-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs. Immunity. 2017 08 15; 47(2):251-267.e7.
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Effects of maternal treatment with ß-hydroxy-ß-metylbutyrate and 2-oxoglutaric acid on femur development in offspring of minks of the standard dark brown type. J Anim Physiol Anim Nutr (Berl). 2018 Feb; 102(1):e299-e308.
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Metabolic reprogramming of cancer-associated fibroblasts by IDH3a downregulation. Cell Rep. 2015 Mar 03; 10(8):1335-48.
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Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae. Biochemistry. 2012 Jan 10; 51(1):243-56.
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Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. Nature. 2010 Nov 11; 468(7321):330-3.
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OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling. FEBS Lett. 2010 Aug 04; 584(15):3340-7.
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A non-heme iron-mediated chemical demethylation in DNA and RNA. Acc Chem Res. 2009 Apr 21; 42(4):519-29.