Neutrophil Activation
"Neutrophil Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonized particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil.
Descriptor ID |
D018375
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MeSH Number(s) |
G12.425.897
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Concept/Terms |
Neutrophil Activation- Neutrophil Activation
- Activation, Neutrophil
- Activations, Neutrophil
- Neutrophil Activations
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Below are MeSH descriptors whose meaning is more general than "Neutrophil Activation".
Below are MeSH descriptors whose meaning is more specific than "Neutrophil Activation".
This graph shows the total number of publications written about "Neutrophil Activation" by people in this website by year, and whether "Neutrophil Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1998 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 2000 | 0 | 1 | 1 | 2001 | 2 | 0 | 2 | 2002 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Neutrophil Activation" by people in Profiles.
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Parisien M, Lima LV, Dagostino C, El-Hachem N, Drury GL, Grant AV, Huising J, Verma V, Meloto CB, Silva JR, Dutra GGS, Markova T, Dang H, Tessier PA, Slade GD, Nackley AG, Ghasemlou N, Mogil JS, Allegri M, Diatchenko L. Acute inflammatory response via neutrophil activation protects against the development of chronic pain. Sci Transl Med. 2022 May 11; 14(644):eabj9954.
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Tang X, Wang P, Zhang R, Watanabe I, Chang E, Vinayachandran V, Nayak L, Lapping S, Liao S, Madera A, Sweet DR, Luo J, Fei J, Jeong HW, Adams RH, Zhang T, Liao X, Jain MK. KLF2 regulates neutrophil activation and thrombosis in cardiac hypertrophy and heart failure progression. J Clin Invest. 2022 02 01; 132(3).
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Cai S, Kandasamy M, Rahmat JN, Tham SM, Bay BH, Lee YK, Mahendran R. Lactobacillus rhamnosus GG Activation of Dendritic Cells and Neutrophils Depends on the Dose and Time of Exposure. J Immunol Res. 2016; 2016:7402760.
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Straub A, Wendel HP, Azevedo R, Ziemer G. The GP IIb/IIIa inhibitor abciximab (ReoPro) decreases activation and interaction of platelets and leukocytes during in vitro cardiopulmonary bypass simulation. Eur J Cardiothorac Surg. 2005 Apr; 27(4):617-21.
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Sharma L, Melis E, Hickey MJ, Clyne CD, Erlich J, Khachigian LM, Davenport P, Morand E, Carmeliet P, Tipping PG. The cytoplasmic domain of tissue factor contributes to leukocyte recruitment and death in endotoxemia. Am J Pathol. 2004 Jul; 165(1):331-40.
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Savinov AY, Tcherepanov A, Green EA, Flavell RA, Chervonsky AV. Contribution of Fas to diabetes development. Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2):628-32.
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Wendel HP, Hauser N, Briquet F, Ziemer G. Hemocompatibility of medical connectors with biopassive or bioactive surface coatings. J Biomater Appl. 2002 Jul; 17(1):5-17.
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Arcaroli J, Kupfner J, Yum HK, Shenkar R, Park JS, Abraham E. Lipopolysaccharide-induced neutrophil gene expression under in vivo or in vitro conditions. Chest. 2002 Mar; 121(3 Suppl):76S.
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Yum HK, Arcaroli J, Kupfner J, Shenkar R, Penninger JM, Sasaki T, Yang KY, Park JS, Abraham E. Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury. J Immunol. 2001 Dec 01; 167(11):6601-8.
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Abraham E, Arcaroli J, Shenkar R. Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia. J Immunol. 2001 Jan 01; 166(1):522-30.
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