 Charybdotoxin
"Charybdotoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 37-amino acid residue peptide isolated from the scorpion Leiurus quinquestriatus hebraeus. It is a neurotoxin that inhibits calcium activated potassium channels.
| Descriptor ID |
D018999
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| MeSH Number(s) |
D12.644.115 D20.888.065.830.150 D23.946.833.065.830.150
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| Concept/Terms |
Charybdotoxin- Charybdotoxin
- CTX Toxin
- Toxin, CTX
- Quinquestriatus Toxin
- Toxin, Quinquestriatus
- ChTX
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Below are MeSH descriptors whose meaning is more general than "Charybdotoxin".
Below are MeSH descriptors whose meaning is more specific than "Charybdotoxin".
This graph shows the total number of publications written about "Charybdotoxin" by people in this website by year, and whether "Charybdotoxin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 2000 | 0 | 2 | 2 | | 2003 | 1 | 2 | 3 | | 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Charybdotoxin" by people in Profiles.
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Lotz MM, Wang H, Song JC, Pories SE, Matthews JB. K+ channel inhibition accelerates intestinal epithelial cell wound healing. Wound Repair Regen. 2004 Sep-Oct; 12(5):565-74.
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Chen H, Kim LA, Rajan S, Xu S, Goldstein SA. Charybdotoxin binding in the I(Ks) pore demonstrates two MinK subunits in each channel complex. Neuron. 2003 Sep 25; 40(1):15-23.
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Tamarina NA, Wang Y, Mariotto L, Kuznetsov A, Bond C, Adelman J, Philipson LH. Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses. Diabetes. 2003 Aug; 52(8):2000-6.
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Derst C, Messutat S, Walther C, Eckert M, Heinemann SH, Wicher D. The large conductance Ca2+-activated potassium channel (pSlo) of the cockroach Periplaneta americana: structure, localization in neurons and electrophysiology. Eur J Neurosci. 2003 Mar; 17(6):1197-212.
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Michelakis E, Rebeyka I, Bateson J, Olley P, Puttagunta L, Archer S. Voltage-gated potassium channels in human ductus arteriosus. Lancet. 2000 Jul 08; 356(9224):134-7.
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Weiger TM, Holmqvist MH, Levitan IB, Clark FT, Sprague S, Huang WJ, Ge P, Wang C, Lawson D, Jurman ME, Glucksmann MA, Silos-Santiago I, DiStefano PS, Curtis R. A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels. J Neurosci. 2000 May 15; 20(10):3563-70.
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Lipkind GM, Fozzard HA. A model of scorpion toxin binding to voltage-gated K+ channels. J Membr Biol. 1997 Aug 01; 158(3):187-96.
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Cornfield DN, Reeve HL, Tolarova S, Weir EK, Archer S. Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):8089-94.
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Archer SL, Huang JM, Hampl V, Nelson DP, Shultz PJ, Weir EK. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7583-7.
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