Sodium-Glucose Transporter 1
"Sodium-Glucose Transporter 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The founding member of the sodium glucose transport proteins. It is predominately expressed in the INTESTINAL MUCOSA of the SMALL INTESTINE.
| Descriptor ID |
D051269
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| MeSH Number(s) |
D12.776.157.530.450.625.437.500 D12.776.157.530.500.750.500 D12.776.157.530.937.696 D12.776.543.585.450.625.562.500 D12.776.543.585.500.750.500 D12.776.543.585.937.821
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| Concept/Terms |
Sodium-Glucose Transporter 1- Sodium-Glucose Transporter 1
- Sodium Glucose Transporter 1
- SLC5A1 Protein
- Sodium-Glucose Cotransporter 1
- Sodium Glucose Cotransporter 1
- SGLT1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Sodium-Glucose Transporter 1".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Glucose Transporter 1".
This graph shows the total number of publications written about "Sodium-Glucose Transporter 1" by people in this website by year, and whether "Sodium-Glucose Transporter 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 3 | 3 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Glucose Transporter 1" by people in Profiles.
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KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state. J Endocrinol. 2014 Aug; 222(2):191-200.
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D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. Gastroenterology. 2011 Feb; 140(2):560-71.
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SGLT-1-mediated glucose uptake protects human intestinal epithelial cells against Giardia duodenalis-induced apoptosis. Int J Parasitol. 2008 Jul; 38(8-9):923-34.
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LPS/CD14 activation triggers SGLT-1-mediated glucose uptake and cell rescue in intestinal epithelial cells via early apoptotic signals upstream of caspase-3. Exp Cell Res. 2006 Oct 15; 312(17):3276-86.
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MAPKAPK-2 is a critical signaling intermediate in NHE3 activation following Na+-glucose cotransport. J Biol Chem. 2006 Aug 25; 281(34):24247-53.
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SGLT-1-mediated glucose uptake protects intestinal epithelial cells against LPS-induced apoptosis and barrier defects: a novel cellular rescue mechanism? FASEB J. 2005 Nov; 19(13):1822-35.
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Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine. Am J Physiol Gastrointest Liver Physiol. 2005 Dec; 289(6):G1007-14.
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Perturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter. J Gen Physiol. 2005 Jan; 125(1):13-36.
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Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation. J Biol Chem. 2005 Jan 14; 280(2):1688-95.
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Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9485-90.