Solute Carrier Organic Anion Transporter Family Member 1B3
"Solute Carrier Organic Anion Transporter Family Member 1B3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.
| Descriptor ID |
D000074542
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| MeSH Number(s) |
D12.776.157.530.450.074.500.781.875 D12.776.157.530.937.905 D12.776.543.585.450.074.500.875.875 D12.776.543.585.937.950
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| Concept/Terms |
Solute Carrier Organic Anion Transporter Family Member 1B3- Solute Carrier Organic Anion Transporter Family Member 1B3
- OATP8 Protein
- Solute Carrier Family 21 Member 8 Protein
- Liver-Specific Organic Anion Transporter-2
- Liver Specific Organic Anion Transporter 2
- OATP1B3 Protein
- SLC21A8 Protein
- SLCO1B3 Protein
|
Below are MeSH descriptors whose meaning is more general than "Solute Carrier Organic Anion Transporter Family Member 1B3".
Below are MeSH descriptors whose meaning is more specific than "Solute Carrier Organic Anion Transporter Family Member 1B3".
This graph shows the total number of publications written about "Solute Carrier Organic Anion Transporter Family Member 1B3" by people in this website by year, and whether "Solute Carrier Organic Anion Transporter Family Member 1B3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Solute Carrier Organic Anion Transporter Family Member 1B3" by people in Profiles.
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Structure of human drug transporters OATP1B1 and OATP1B3. Nat Commun. 2023 09 18; 14(1):5774.
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The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance). Pharmacogenet Genomics. 2013 Jan; 23(1):29-33.
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Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia. Cancer Sci. 2008 May; 99(5):967-72.