 Alkyl and Aryl Transferases
"Alkyl and Aryl Transferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A somewhat heterogeneous class of enzymes that catalyze the transfer of alkyl or related groups (excluding methyl groups). EC 2.5.
| Descriptor ID |
D019883
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| MeSH Number(s) |
D08.811.913.225
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alkyl and Aryl Transferases".
Below are MeSH descriptors whose meaning is more specific than "Alkyl and Aryl Transferases".
This graph shows the total number of publications written about "Alkyl and Aryl Transferases" by people in this website by year, and whether "Alkyl and Aryl Transferases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1994 | 2 | 0 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 2003 | 1 | 2 | 3 | | 2005 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Alkyl and Aryl Transferases" by people in Profiles.
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Moon JH, Park AK, Jang EH, Kim HS, Chi YM. Crystal structure of a PduO-type ATP:cobalamin adenosyltransferase from Burkholderia thailandensis. Proteins. 2008 Aug 15; 72(3):1066-70.
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Duguid EM, Rice PA, He C. The structure of the human AGT protein bound to DNA and its implications for damage detection. J Mol Biol. 2005 Jul 22; 350(4):657-66.
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Duguid EM, Mishina Y, He C. How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases. Chem Biol. 2003 Sep; 10(9):827-35.
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Vokes EE, Choy H. Targeted therapies for stage III non-small cell lung cancer: integration in the combined modality setting. Lung Cancer. 2003 Aug; 41 Suppl 1:S115-21.
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Adjei AA, Mauer A, Bruzek L, Marks RS, Hillman S, Geyer S, Hanson LJ, Wright JJ, Erlichman C, Kaufmann SH, Vokes EE. Phase II study of the farnesyl transferase inhibitor R115777 in patients with advanced non-small-cell lung cancer. J Clin Oncol. 2003 May 01; 21(9):1760-6.
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Cai Y, Wu MH, Ludeman SM, Grdina DJ, Dolan ME. Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity. Cancer Res. 1999 Jul 01; 59(13):3059-63.
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Dolan ME, Roy SK, Fasanmade AA, Paras PR, Schilsky RL, Ratain MJ. O6-benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings. J Clin Oncol. 1998 May; 16(5):1803-10.
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Kurpad SN, Dolan ME, McLendon RE, Archer GE, Moschel RC, Pegg AE, Bigner DD, Friedman HS. Intraarterial O6-benzylguanine enables the specific therapy of nitrosourea-resistant intracranial human glioma xenografts in athymic rats with 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer Chemother Pharmacol. 1997; 39(4):307-16.
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Reinbothe C, Ortel B, Parthier B, Reinbothe S. Cytosolic and plastid forms of 5-enolpyruvylshikimate-3-phosphate synthase in Euglena gracilis are differentially expressed during light-induced chloroplast development. Mol Gen Genet. 1994 Dec 01; 245(5):616-22.
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Friedman HS, Dolan ME, Kaufmann SH, Colvin OM, Griffith OW, Moschel RC, Schold SC, Bigner DD, Ali-Osman F. Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan. Cancer Res. 1994 Jul 01; 54(13):3487-93.
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