"Spermine Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to spermidine in the biosynthesis of spermine. It has an acidic isoelectric point at pH 5.0. EC 2.5.1.22.
| Descriptor ID |
D013097
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| MeSH Number(s) |
D08.811.913.225.912
|
| Concept/Terms |
Spermine Synthase- Spermine Synthase
- Synthase, Spermine
- Spermine Synthetase
- Synthetase, Spermine
- Spermidine Aminopropyltransferase
- Aminopropyltransferase, Spermidine
|
Below are MeSH descriptors whose meaning is more general than "Spermine Synthase".
Below are MeSH descriptors whose meaning is more specific than "Spermine Synthase".
This graph shows the total number of publications written about "Spermine Synthase" by people in this website by year, and whether "Spermine Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spermine Synthase" by people in Profiles.
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Reduction of spermine synthase enhances autophagy to suppress Tau accumulation. Cell Death Dis. 2024 May 13; 15(5):333.
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Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome. EMBO Mol Med. 2023 11 08; 15(11):e17833.
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Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome. Nat Commun. 2017 Nov 02; 8(1):1257.