"Inflammasomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
| Descriptor ID |
D058847
|
| MeSH Number(s) |
D05.500.224
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Inflammasomes".
Below are MeSH descriptors whose meaning is more specific than "Inflammasomes".
This graph shows the total number of publications written about "Inflammasomes" by people in this website by year, and whether "Inflammasomes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 2 | 3 | 5 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Inflammasomes" by people in Profiles.
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Identification of CDK4/6 Inhibitors as Small Molecule NLRP3 Inflammasome Activators that Facilitate IL-1ß Secretion and T Cell Adjuvanticity. J Med Chem. 2024 Sep 12; 67(17):14974-14985.
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Palmitoylation at a conserved cysteine residue facilitates gasdermin D-mediated pyroptosis and cytokine release. Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29):e2400883121.
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Glyburide confers neuroprotection against age-related macular degeneration (AMD). Transl Res. 2024 Oct; 272:81-94.
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Epithelial IFN? signalling and compartmentalized antigen presentation orchestrate gut immunity. Nature. 2023 Nov; 623(7989):1044-1052.
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Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span. Aging (Albany NY). 2023 07 23; 15(14):6658-6689.
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Endosomal trafficking of two-pore K+ efflux channel TWIK2 to plasmalemma mediates NLRP3 inflammasome activation and inflammatory injury. Elife. 2023 05 09; 12.
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Nanovaccine that activates the NLRP3 inflammasome enhances tumor specific activation of anti-cancer immunity. Biomaterials. 2023 05; 296:122062.
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Size matters in non-canonical inflammasome activation and cell-mediated immunity. Cell Rep Med. 2023 01 17; 4(1):100904.
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Effects of Vitamin D Supplementation on Adipose Tissue Inflammation and NF-?B/AMPK Activation in Obese Mice Fed a High-Fat Diet. Int J Mol Sci. 2022 Sep 18; 23(18).
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Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2022 09 01; 206(5):608-624.