"Inflammasomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
| Descriptor ID |
D058847
|
| MeSH Number(s) |
D05.500.224
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Inflammasomes".
Below are MeSH descriptors whose meaning is more specific than "Inflammasomes".
This graph shows the total number of publications written about "Inflammasomes" by people in this website by year, and whether "Inflammasomes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2021 | 3 | 0 | 3 |
| 2022 | 0 | 2 | 2 |
| 2023 | 2 | 4 | 6 |
| 2024 | 3 | 1 | 4 |
| 2025 | 1 | 3 | 4 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Inflammasomes" by people in Profiles.
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Sensing the spectrum: diverse stimuli for the NLRP3 inflammasome. Commun Biol. 2026 05 20; 9(1).
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Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment. J Clin Invest. 2026 02 02; 136(3).
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Type A cholesterol-dependent cytolysins translocate to the trans-Golgi network for NLRP3 inflammasome activation. Nat Immunol. 2025 Oct; 26(10):1673-1685.
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Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae. Science. 2025 03 07; 387(6738):eadq2509.
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NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 02 11; 58(2):326-343.e11.
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The human disease-associated gene ZNFX1 controls inflammation through inhibition of the NLRP3 inflammasome. EMBO J. 2024 Nov; 43(22):5469-5493.
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Identification of CDK4/6 Inhibitors as Small Molecule NLRP3 Inflammasome Activators that Facilitate IL-1ß Secretion and T Cell Adjuvanticity. J Med Chem. 2024 09 12; 67(17):14974-14985.
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Palmitoylation at a conserved cysteine residue facilitates gasdermin D-mediated pyroptosis and cytokine release. Proc Natl Acad Sci U S A. 2024 07 16; 121(29):e2400883121.
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Glyburide confers neuroprotection against age-related macular degeneration (AMD). Transl Res. 2024 10; 272:81-94.
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NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation. Cell Rep. 2024 04 23; 43(4):114070.