Axin Signaling Complex

"Axin Signaling Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.

Descriptor ID	D060465
MeSH Number(s)	D05.500.117 D12.776.476.081
Concept/Terms	Axin Signaling Complex Axin Signaling Complex Signaling Complex, Axin Axin Signaling Complex Proteins beta-Catenin Destruction Complex Destruction Complex, beta-Catenin beta Catenin Destruction Complex

Below are MeSH descriptors whose meaning is more general than "Axin Signaling Complex".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Multiprotein Complexes [D05.500]
Axin Signaling Complex [D05.500.117]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Axin Signaling Complex [D12.776.476.081]

Below are MeSH descriptors whose meaning is related to "Axin Signaling Complex".

Below are MeSH descriptors whose meaning is more specific than "Axin Signaling Complex".

publications

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