 Methylenetetrahydrofolate Reductase (NADPH2)
"Methylenetetrahydrofolate Reductase (NADPH2)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.
| Descriptor ID |
D042965
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| MeSH Number(s) |
D08.811.682.662.290 D12.776.331.775
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| Concept/Terms |
Methylenetetrahydrofolate Reductase (NADPH2)- Methylenetetrahydrofolate Reductase (NADPH2)
- Methylenetetrahydrofolate Reductase (NADPH)
- Methylene-THF Reductase (NADPH)
- Methylenetetrahydrofolate Reductase
- 5,10-Methylenetetrahydrofolate Reductase (NADPH)
- Methylene Tetrahydrofolate Reductase
- Tetrahydrofolate Reductase, Methylene
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Below are MeSH descriptors whose meaning is more general than "Methylenetetrahydrofolate Reductase (NADPH2)".
Below are MeSH descriptors whose meaning is more specific than "Methylenetetrahydrofolate Reductase (NADPH2)".
This graph shows the total number of publications written about "Methylenetetrahydrofolate Reductase (NADPH2)" by people in this website by year, and whether "Methylenetetrahydrofolate Reductase (NADPH2)" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 2 | 0 | 2 | | 2011 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methylenetetrahydrofolate Reductase (NADPH2)" by people in Profiles.
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Chai W, Zhang Z, Ni M, Geng P, Lian Z, Zhang G, Shi LL, Chen J. Genetic association between methylenetetrahydrofolate reductase gene polymorphism and risk of osteonecrosis of the femoral head. Biomed Res Int. 2015; 2015:196495.
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Nagele P, Brown F, Francis A, Scott MG, Gage BF, Miller JP. In reply. Anesthesiology. 2014 Feb; 120(2):515-6.
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Nagele P, Brown F, Francis A, Scott MG, Gage BF, Miller JP. Influence of nitrous oxide anesthesia, B-vitamins, and MTHFR gene polymorphisms on perioperative cardiac events: the vitamins in nitrous oxide (VINO) randomized trial. Anesthesiology. 2013 Jul; 119(1):19-28.
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Nagele P, Meissner K, Francis A, Födinger M, Saccone NL. Genetic and environmental determinants of plasma total homocysteine levels: impact of population-wide folate fortification. Pharmacogenet Genomics. 2011 Jul; 21(7):426-31.
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Woloszynska-Read A, Zhang W, Yu J, Link PA, Mhawech-Fauceglia P, Collamat G, Akers SN, Ostler KR, Godley LA, Odunsi K, Karpf AR. Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage. Clin Cancer Res. 2011 Apr 15; 17(8):2170-80.
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Barker SD, Bale S, Booker J, Buller A, Das S, Friedman K, Godwin AK, Grody WW, Highsmith E, Kant JA, Lyon E, Mao R, Monaghan KG, Payne DA, Pratt VM, Schrijver I, Shrimpton AE, Spector E, Telatar M, Toji L, Weck K, Zehnbauer B, Kalman LV. Development and characterization of reference materials for MTHFR, SERPINA1, RET, BRCA1, and BRCA2 genetic testing. J Mol Diagn. 2009 Nov; 11(6):553-61.
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Ravel C, Chantot-Bastaraud S, Chalmey C, Barreiro L, Aknin-Seifer I, Pfeffer J, Berthaut I, Mathieu EE, Mandelbaum J, Siffroi JP, McElreavey K, Bashamboo A. Lack of association between genetic polymorphisms in enzymes associated with folate metabolism and unexplained reduced sperm counts. PLoS One. 2009 Aug 06; 4(8):e6540.
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Kohli U, Arora S, Kabra M, Ramakrishnan L, Gulati S, Pandey RM. Prevalence of MTHFR C677T polymorphism in north Indian mothers having babies with Trisomy 21 Down syndrome. Downs Syndr Res Pract. 2008 Oct; 12(2):133-7.
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Nagele P, Zeugswetter B, Wiener C, Burger H, Hüpfl M, Mittlböck M, Födinger M. Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia. Anesthesiology. 2008 Jul; 109(1):36-43.
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Eldibany MM, Caprini JA. Hyperhomocysteinemia and thrombosis: an overview. Arch Pathol Lab Med. 2007 Jun; 131(6):872-84.
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