 Endothelin-1
"Endothelin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
| Descriptor ID |
D019332
|
| MeSH Number(s) |
D12.644.276.400.225 D12.776.467.400.225 D23.529.400.225
|
| Concept/Terms |
Endothelin-1- Endothelin-1
- Endothelin 1
- Endothelin Type 1
- ET-1 (Endothelin-1)
Proendothelin (1-38)- Proendothelin (1-38)
- Big Endothelin
- Big Endothelin-1
- Big Endothelin 1
- Endothelin-1, Big
- Endothelin, Big
Preproendothelin-1- Preproendothelin-1
- Preproendothelin 1
- Preproendothelin
- Proendothelin-1 Precursor
- Precursor, Proendothelin-1
- Proendothelin 1 Precursor
|
Below are MeSH descriptors whose meaning is more general than "Endothelin-1".
Below are MeSH descriptors whose meaning is more specific than "Endothelin-1".
This graph shows the total number of publications written about "Endothelin-1" by people in this website by year, and whether "Endothelin-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 2 | 1 | 3 | | 2001 | 2 | 0 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 2 | 4 | | 2007 | 2 | 0 | 2 | | 2008 | 2 | 1 | 3 | | 2009 | 1 | 1 | 2 | | 2011 | 2 | 0 | 2 | | 2012 | 2 | 0 | 2 | | 2013 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Endothelin-1" by people in Profiles.
-
Wu D, Hamanaka RB, Fang Y, Mutlu GM. Letter by Wu et al Regarding Article, "Mechanical Activation of Hypoxia-Inducible Factor 1a Drives Endothelial Dysfunction at Atheroprone Sites". Arterioscler Thromb Vasc Biol. 2017 12; 37(12):e197-e198.
-
Lin J, Chudasama N, Hayashi Y, Hawk C, Ramnauth SD, Wong KY, Harxhi A, Onat D, Wakabayashi M, Uriel N, Jorde UP, LeJemtel TH, Sabbah HN, Demmer RT, Colombo PC. Peripheral venous congestion causes time- and dose-dependent release of endothelin-1 in humans. Physiol Rep. 2017 Mar; 5(6).
-
Luo K, Thaete LG, Neerhof MG. Endothelin Receptor A Antagonism and Fetal Growth in Endothelial Nitric Oxide Synthase Gene Knockout Maternal and Fetal Mice. Reprod Sci. 2016 08; 23(8):1028-36.
-
Benza RL, Gomberg-Maitland M, Demarco T, Frost AE, Torbicki A, Langleben D, Pulido T, Correa-Jaque P, Passineau MJ, Wiener HW, Tamari M, Hirota T, Kubo M, Tiwari HK. Endothelin-1 Pathway Polymorphisms and Outcomes in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1345-54.
-
Kitazawa T, Takechi M, Hirasawa T, Adachi N, Narboux-Nême N, Kume H, Maeda K, Hirai T, Miyagawa-Tomita S, Kurihara Y, Hitomi J, Levi G, Kuratani S, Kurihara H. Developmental genetic bases behind the independent origin of the tympanic membrane in mammals and diapsids. Nat Commun. 2015 Apr 22; 6:6853.
-
Peng YJ, Nanduri J, Raghuraman G, Wang N, Kumar GK, Prabhakar NR. Role of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia. Exp Physiol. 2013 Nov; 98(11):1620-30.
-
Nagendran J, Sutendra G, Paterson I, Champion HC, Webster L, Chiu B, Haromy A, Rebeyka IM, Ross DB, Michelakis ED. Endothelin axis is upregulated in human and rat right ventricular hypertrophy. Circ Res. 2013 Jan 18; 112(2):347-54.
-
Maron BA, Zhang YY, White K, Chan SY, Handy DE, Mahoney CE, Loscalzo J, Leopold JA. Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension. Circulation. 2012 Aug 21; 126(8):963-74.
-
Neerhof MG, Khan S, Synowiec S, Qu XW, Thaete LG. The significance of endothelin in platelet-activating factor-induced fetal growth restriction. Reprod Sci. 2012 Nov; 19(11):1175-80.
-
Peng YJ, Nanduri J, Zhang X, Wang N, Raghuraman G, Seagard J, Kumar GK, Prabhakar NR. Endothelin-1 mediates attenuated carotid baroreceptor activity by intermittent hypoxia. J Appl Physiol (1985). 2012 Jan; 112(1):187-96.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|