"DNA Footprinting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
| Descriptor ID |
D018983
|
| MeSH Number(s) |
E05.393.300
|
| Concept/Terms |
DNA Footprinting- DNA Footprinting
- DNA Footprintings
- Footprinting, DNA
- Footprintings, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Footprinting".
Below are MeSH descriptors whose meaning is more specific than "DNA Footprinting".
This graph shows the total number of publications written about "DNA Footprinting" by people in this website by year, and whether "DNA Footprinting" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 2 | 3 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Footprinting" by people in Profiles.
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Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. Cell Stem Cell. 2017 09 07; 21(3):305-318.e8.
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Regulatory evolution of Tbx5 and the origin of paired appendages. Proc Natl Acad Sci U S A. 2016 09 06; 113(36):10115-20.
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Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding? PLoS Genet. 2016 Feb; 12(2):e1005875.
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The bacterial response regulator ArcA uses a diverse binding site architecture to regulate carbon oxidation globally. PLoS Genet. 2013; 9(10):e1003839.
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The accessible chromatin landscape of the human genome. Nature. 2012 Sep 06; 489(7414):75-82.
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G-quadruplex and i-motif are mutually exclusive in ILPR double-stranded DNA. Biophys J. 2012 Jun 06; 102(11):2575-84.
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The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression. J Bacteriol. 2012 Jun; 194(12):3098-108.
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DNase?I sensitivity QTLs are a major determinant of human expression variation. Nature. 2012 Feb 05; 482(7385):390-4.
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c-Jun and c-Fos regulate the complement factor H promoter in murine astrocytes. Mol Immunol. 2011 Oct; 49(1-2):201-10.
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In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS. J Bacteriol. 2010 Apr; 192(8):2111-27.