 Potassium Channels, Inwardly Rectifying
"Potassium Channels, Inwardly Rectifying" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Potassium channels where the flow of K+ ions into the cell is greater than the outward flow.
| Descriptor ID |
D024661
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| MeSH Number(s) |
D12.776.157.530.400.600.450 D12.776.543.550.425.750.450 D12.776.543.585.400.750.450
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| Concept/Terms |
Potassium Channels, Inwardly Rectifying- Potassium Channels, Inwardly Rectifying
- Potassium Channel, Inwardly Rectifying
- Inward Rectifier K+ Channel
- IRK1 Channel
- Channel, IRK1
- Inward Rectifier Potassium Channel
- Inward Rectifier Potassium Channels
- Inwardly Rectifying Postassium Channels
- Inwardly Rectifying Potassium Channel
- K+ Channels, Inwardly Rectifying
- Inward Rectifier K+ Channels
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Below are MeSH descriptors whose meaning is more general than "Potassium Channels, Inwardly Rectifying".
Below are MeSH descriptors whose meaning is more specific than "Potassium Channels, Inwardly Rectifying".
This graph shows the total number of publications written about "Potassium Channels, Inwardly Rectifying" by people in this website by year, and whether "Potassium Channels, Inwardly Rectifying" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1994 | 1 | 0 | 1 | | 1995 | 4 | 0 | 4 | | 1996 | 3 | 0 | 3 | | 1997 | 2 | 0 | 2 | | 1998 | 3 | 0 | 3 | | 1999 | 3 | 0 | 3 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 2 | 1 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 3 | 1 | 4 | | 2006 | 2 | 2 | 4 | | 2007 | 3 | 1 | 4 | | 2008 | 1 | 0 | 1 | | 2009 | 3 | 0 | 3 | | 2010 | 1 | 1 | 2 | | 2011 | 1 | 1 | 2 | | 2012 | 3 | 1 | 4 | | 2013 | 2 | 0 | 2 | | 2014 | 0 | 3 | 3 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 2 | 1 | 3 | | 2018 | 4 | 0 | 4 | | 2019 | 1 | 0 | 1 | | 2020 | 3 | 0 | 3 | | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Potassium Channels, Inwardly Rectifying" by people in Profiles.
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Dalgin G, Tryba AK, Cohen AP, Park SY, Philipson LH, Greeley SAW, Garcia AJ. Developmental defects and impaired network excitability in a cerebral organoid model of KCNJ11 p.V59M-related neonatal diabetes. Sci Rep. 2021 11 03; 11(1):21590.
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Déri S, Borbás J, Hartai T, Hategan L, Csányi B, Visnyovszki Á, Madácsy T, Maléth J, Hegedus Z, Nagy I, Arora R, Labro AJ, Környei L, Varró A, Sepp R, Ördög B. Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient. Cardiovasc Res. 2021 07 07; 117(8):1923-1934.
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Bowman P, Mathews F, Barbetti F, Shepherd MH, Sanchez J, Piccini B, Beltrand J, Letourneau-Freiberg LR, Polak M, Greeley SAW, Rawlins E, Babiker T, Thomas NJ, De Franco E, Ellard S, Flanagan SE, Hattersley AT. Long-term Follow-up of Glycemic and Neurological Outcomes in an International Series of Patients With Sulfonylurea-Treated ABCC8 Permanent Neonatal Diabetes. Diabetes Care. 2021 01; 44(1):35-42.
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Clark MD, Contreras GF, Shen R, Perozo E. Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1. Nature. 2020 07; 583(7814):145-149.
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De Franco E, Saint-Martin C, Brusgaard K, Knight Johnson AE, Aguilar-Bryan L, Bowman P, Arnoux JB, Larsen AR, Sanyoura M, Greeley SAW, Calzada-León R, Harman B, Houghton JAL, Nishimura-Meguro E, Laver TW, Ellard S, Del Gaudio D, Christesen HT, Bellanné-Chantelot C, Flanagan SE. Update of variants identified in the pancreatic ß-cell KATP channel genes KCNJ11 and ABCC8 in individuals with congenital hyperinsulinism and diabetes. Hum Mutat. 2020 05; 41(5):884-905.
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Letourneau LR, Greeley SAW. Precision Medicine: Long-Term Treatment with Sulfonylureas in Patients with Neonatal Diabetes Due to KCNJ11 Mutations. Curr Diab Rep. 2019 06 27; 19(8):52.
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Murase M, Seino Y, Maekawa R, Iida A, Hosokawa K, Hayami T, Tsunekawa S, Hamada Y, Yokoi N, Seino S, Hayashi Y, Arima H. Functional adenosine triphosphate-sensitive potassium channel is required in high-carbohydrate diet-induced increase in ß-cell mass. J Diabetes Investig. 2019 Mar; 10(2):238-250.
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Fancher IS, Ahn SJ, Adamos C, Osborn C, Oh MJ, Fang Y, Reardon CA, Getz GS, Phillips SA, Levitan I. Hypercholesterolemia-Induced Loss of Flow-Induced Vasodilation and Lesion Formation in Apolipoprotein E-Deficient Mice Critically Depend on Inwardly Rectifying K+ Channels. J Am Heart Assoc. 2018 03 03; 7(5).
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Nanazashvili M, Sánchez-Rodríguez JE, Fosque B, Bezanilla F, Sackin H. LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b. Biophys J. 2018 01 09; 114(1):88-97.
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Sanyoura M, Jacobsen L, Carmody D, Del Gaudio D, Alkorta-Aranburu G, Arndt K, Hu Y, Kobiernicki F, Kusmartseva I, Atkinson MA, Philipson LH, Schatz D, Campbell-Thompson M, Greeley SAW. Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA. J Clin Endocrinol Metab. 2018 01 01; 103(1):35-45.
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