 Mechanotransduction, Cellular
"Mechanotransduction, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.
| Descriptor ID |
D040542
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| MeSH Number(s) |
G01.154.100.440 G01.595.100.440 G02.111.087.800.580 G02.149.115.800.580 G04.299.880.580
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| Concept/Terms |
Mechanotransduction, Cellular- Mechanotransduction, Cellular
- Signal Transduction, Mechanical
- Mechanical Signal Transduction
- Mechanosensory Transduction
- Transduction, Mechanosensory
- Cellular Mechanotransduction
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Below are MeSH descriptors whose meaning is more general than "Mechanotransduction, Cellular".
Below are MeSH descriptors whose meaning is more specific than "Mechanotransduction, Cellular".
This graph shows the total number of publications written about "Mechanotransduction, Cellular" by people in this website by year, and whether "Mechanotransduction, Cellular" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2003 | 2 | 0 | 2 | | 2004 | 1 | 0 | 1 | | 2005 | 5 | 0 | 5 | | 2006 | 3 | 1 | 4 | | 2007 | 3 | 1 | 4 | | 2009 | 1 | 2 | 3 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 3 | 0 | 3 | | 2013 | 3 | 0 | 3 | | 2014 | 2 | 1 | 3 | | 2015 | 2 | 2 | 4 | | 2016 | 3 | 0 | 3 | | 2017 | 2 | 2 | 4 | | 2018 | 2 | 4 | 6 | | 2019 | 5 | 1 | 6 | | 2020 | 2 | 0 | 2 | | 2021 | 1 | 1 | 2 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mechanotransduction, Cellular" by people in Profiles.
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Romani P, Nirchio N, Arboit M, Barbieri V, Tosi A, Michielin F, Shibuya S, Benoist T, Wu D, Hindmarch CCT, Giomo M, Urciuolo A, Giamogante F, Roveri A, Chakravarty P, Montagner M, Calì T, Elvassore N, Archer SL, De Coppi P, Rosato A, Martello G, Dupont S. Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance. Nat Cell Biol. 2022 02; 24(2):168-180.
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Li J, Fang Y, Wu D. Mechanical forces and metabolic changes cooperate to drive cellular memory and endothelial phenotypes. Curr Top Membr. 2021; 87:199-253.
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Mallis RJ, Duke-Cohan JS, Das DK, Akitsu A, Luoma AM, Banik D, Stephens HM, Tetteh PW, Castro CD, Krahnke S, Hussey RE, Lawney B, Brazin KN, Reche PA, Hwang W, Adams EJ, Lang MJ, Reinherz EL. Molecular design of the ?dT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing. Proc Natl Acad Sci U S A. 2021 06 29; 118(26).
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Cavanaugh KE, Staddon MF, Banerjee S, Gardel ML. Adaptive viscoelasticity of epithelial cell junctions: from models to methods. Curr Opin Genet Dev. 2020 08; 63:86-94.
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Mehta V, Pang KL, Rozbesky D, Nather K, Keen A, Lachowski D, Kong Y, Karia D, Ameismeier M, Huang J, Fang Y, Del Rio Hernandez A, Reader JS, Jones EY, Tzima E. The guidance receptor plexin D1 is a mechanosensor in endothelial cells. Nature. 2020 02; 578(7794):290-295.
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Reddy B, Bavi N, Lu A, Park Y, Perozo E. Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS. Elife. 2019 12 27; 8.
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Cavanaugh KE, Staddon MF, Munro E, Banerjee S, Gardel ML. RhoA Mediates Epithelial Cell Shape Changes via Mechanosensitive Endocytosis. Dev Cell. 2020 01 27; 52(2):152-166.e5.
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Staddon MF, Cavanaugh KE, Munro EM, Gardel ML, Banerjee S. Mechanosensitive Junction Remodeling Promotes Robust Epithelial Morphogenesis. Biophys J. 2019 11 05; 117(9):1739-1750.
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Dent LG, Manning SA, Kroeger B, Williams AM, Saiful Hilmi AJ, Crea L, Kondo S, Horne-Badovinac S, Harvey KF. The dPix-Git complex is essential to coordinate epithelial morphogenesis and regulate myosin during Drosophila egg chamber development. PLoS Genet. 2019 05; 15(5):e1008083.
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Fang Y, Wu D, Birukov KG. Mechanosensing and Mechanoregulation of Endothelial Cell Functions. Compr Physiol. 2019 03 15; 9(2):873-904.
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