 Genes, RAG-1
"Genes, RAG-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes involved in activating the enzyme VDJ recombinase. RAG-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in maturing lymphocytes.
| Descriptor ID |
D016654
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| MeSH Number(s) |
G05.360.340.024.340.400
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| Concept/Terms |
Genes, RAG-1- Genes, RAG-1
- Genes, RAG 1
- Recombination-Activating Genes-1
- Recombination Activating Genes 1
- Recombination-Activating Gene-1
- Recombination Activating Gene 1
- RAG-1 Genes
- Gene, RAG-1
- RAG 1 Genes
- RAG-1 Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, RAG-1".
Below are MeSH descriptors whose meaning is more specific than "Genes, RAG-1".
This graph shows the total number of publications written about "Genes, RAG-1" by people in this website by year, and whether "Genes, RAG-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, RAG-1" by people in Profiles.
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Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, Gounari F. ß-Catenin induces T-cell transformation by promoting genomic instability. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):391-6.
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Arina A, Murillo O, Dubrot J, Azpilikueta A, Gabari I, Perez-Gracia JL, Alfaro C, Berasain C, Prieto J, Ferrini S, Hervas-Stubbs S, Melero I. Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells. Gene Ther. 2008 Apr; 15(7):473-83.
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Brown IE, Blank C, Kline J, Kacha AK, Gajewski TF. Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection. J Immunol. 2006 Oct 01; 177(7):4521-9.
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Blair C, Naclerio RM, Yu X, Thompson K, Sperling A. Role of type 1 T helper cells in the resolution of acute Streptococcus pneumoniae sinusitis: a mouse model. J Infect Dis. 2005 Oct 01; 192(7):1237-44.
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Tumanov A, Kuprash D, Lagarkova M, Grivennikov S, Abe K, Shakhov A, Drutskaya L, Stewart C, Chervonsky A, Nedospasov S. Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity. 2002 Sep; 17(3):239-50.
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Yannoutsos N, Wilson P, Yu W, Chen HT, Nussenzweig A, Petrie H, Nussenzweig MC. The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo. J Exp Med. 2001 Aug 20; 194(4):471-80.
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Manning TC, Rund LA, Gruber MM, Fallarino F, Gajewski TF, Kranz DM. Antigen recognition and allogeneic tumor rejection in CD8+ TCR transgenic/RAG(-/-) mice. J Immunol. 1997 Nov 15; 159(10):4665-75.
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Fuller K, Storb U. Identification and characterization of the murine Rag1 promoter. Mol Immunol. 1997 Aug-Sep; 34(12-13):939-54.
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