Lymphocytes, Tumor-Infiltrating
"Lymphocytes, Tumor-Infiltrating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer.
| Descriptor ID |
D016246
|
| MeSH Number(s) |
A11.118.637.555.567.650 A15.145.229.637.555.567.650 A15.382.490.555.567.650
|
| Concept/Terms |
Lymphocytes, Tumor-Infiltrating- Lymphocytes, Tumor-Infiltrating
- Lymphocytes, Tumor Infiltrating
- Tumor-Infiltrating Lymphocytes
- Lymphocyte, Tumor-Infiltrating
- Tumor Infiltrating Lymphocytes
- Tumor-Infiltrating Lymphocyte
Tumor-Derived Activated Cells- Tumor-Derived Activated Cells
- Activated Cell, Tumor-Derived
- Activated Cells, Tumor-Derived
- Tumor Derived Activated Cells
- Tumor-Derived Activated Cell
|
Below are MeSH descriptors whose meaning is more general than "Lymphocytes, Tumor-Infiltrating".
Below are MeSH descriptors whose meaning is more specific than "Lymphocytes, Tumor-Infiltrating".
This graph shows the total number of publications written about "Lymphocytes, Tumor-Infiltrating" by people in this website by year, and whether "Lymphocytes, Tumor-Infiltrating" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 4 | 0 | 4 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 3 | 1 | 4 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 2 | 2 | 4 |
| 2015 | 3 | 1 | 4 |
| 2016 | 3 | 7 | 10 |
| 2017 | 8 | 1 | 9 |
| 2018 | 5 | 4 | 9 |
| 2019 | 5 | 8 | 13 |
| 2020 | 6 | 5 | 11 |
| 2021 | 5 | 6 | 11 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 4 | 6 |
| 2025 | 5 | 2 | 7 |
| 2026 | 2 | 5 | 7 |
To return to the timeline,
click here.
Below are the most recent publications written about "Lymphocytes, Tumor-Infiltrating" by people in Profiles.
-
Tumor-infiltrating lymphocyte (TIL) therapy: Historical context, clinical applications, and future directions. Cancer. 2026 Aug 01; 132(15):e70526.
-
Mitochondrial potential reflects T cell fitness and function during cancer immunotherapy. J Immunol. 2026 Jun 07; 215(6).
-
Potent Cytotoxic Tumor-Infiltrating Lymphocytes Can Be Generated from Immune-Excluded Chondrosarcomas Using Regulatable Membrane-Bound IL15. Cancer Immunol Res. 2026 Jun 02; 14(6):944-957.
-
Integrated Single-Cell Profiling Reveals Dichotomous NK Cell Populations Associated with Immunosuppression in Solid Tumors. Cancer Immunol Res. 2026 Jun 02; 14(6):1008-1021.
-
Targeting the novel immune checkpoint KLRG1 is markedly therapeutic against cancer through multiple lymphocyte subsets. J Immunother Cancer. 2026 Apr 09; 14(4).
-
Regulatory T-cell Sensing of Extracellular ATP via P2RX7 Promotes Their Accumulation and Suppression and Drives Lung Tumor Growth. Cancer Immunol Res. 2026 Apr 02; 14(4):658-675.
-
Glutamine synthetase deficiency enhances CD8 T cell survival and stress resilience in the tumor microenvironment. J Immunol. 2026 01 21; 215(1).
-
The prognostic value of systemic inflammatory response index (SIRI) and CD8?+?tumor-infiltrating lymphocytes for patients with localized undifferentiated pleomorphic sarcoma of soft tissue. BMC Cancer. 2025 Dec 15; 25(1):1870.
-
Efficacy and safety of one-time autologous tumor-infiltrating lymphocyte cell therapy in patients with recurrent and/or metastatic head and neck squamous cell carcinoma. J Immunother Cancer. 2025 Aug 24; 13(8).
-
ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images. Nat Commun. 2025 Aug 16; 16(1):7633.