 Tubulin
"Tubulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE.
| Descriptor ID |
D014404
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| MeSH Number(s) |
D05.750.078.734.800 D12.776.220.600.800 D12.776.641.920
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tubulin".
Below are MeSH descriptors whose meaning is more specific than "Tubulin".
This graph shows the total number of publications written about "Tubulin" by people in this website by year, and whether "Tubulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 1 | 0 | 1 | | 1986 | 1 | 0 | 1 | | 1987 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 1 | 2 | 3 | | 1995 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 6 | 7 | | 2005 | 0 | 3 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 3 | 4 | | 2009 | 0 | 2 | 2 | | 2010 | 3 | 0 | 3 | | 2012 | 2 | 1 | 3 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 2 | 2 | 4 | | 2016 | 0 | 1 | 1 | | 2018 | 2 | 1 | 3 | | 2019 | 0 | 1 | 1 | | 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Tubulin" by people in Profiles.
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Singh H, Chmura J, Bhaumik R, Pandey GN, Rasenick MM. Membrane-Associated a-Tubulin Is Less Acetylated in Postmortem Prefrontal Cortex from Depressed Subjects Relative to Controls: Cytoskeletal Dynamics, HDAC6, and Depression. J Neurosci. 2020 05 13; 40(20):4033-4041.
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Blumkin L, Leibovitz Z, Krajden-Haratz K, Arad A, Yosovich K, Gindes L, Zerem A, Ben-Sira L, Lev D, Nissenkorn A, Kidron D, Dobyns WB, Malinger G, Bahi-Buisson N, Leventer RJ, Lerman-Sagie T. Autosomal dominant TUBB3-related syndrome: Fetal, radiologic, clinical and morphological features. Eur J Paediatr Neurol. 2020 May; 26:46-60.
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Akbarpour M, Wu Q, Liu X, Sun H, Lecuona E, Tomic R, Bhorade S, Mohanakumar T, Bharat A. Clinical relevance of lung-restricted antibodies in lung transplantation. Hum Immunol. 2019 Aug; 80(8):595-601.
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Sebé-Pedrós A, Saudemont B, Chomsky E, Plessier F, Mailhé MP, Renno J, Loe-Mie Y, Lifshitz A, Mukamel Z, Schmutz S, Novault S, Steinmetz PRH, Spitz F, Tanay A, Marlow H. Cnidarian Cell Type Diversity and Regulation Revealed by Whole-Organism Single-Cell RNA-Seq. Cell. 2018 05 31; 173(6):1520-1534.e20.
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Brock S, Stouffs K, Scalais E, D'Hooghe M, Keymolen K, Guerrini R, Dobyns WB, Di Donato N, Jansen AC. Tubulinopathies continued: refining the phenotypic spectrum associated with variants in TUBG1. Eur J Hum Genet. 2018 08; 26(8):1132-1142.
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Singh H, Wray N, Schappi JM, Rasenick MM. Disruption of lipid-raft localized Gas/tubulin complexes by antidepressants: a unique feature of HDAC6 inhibitors, SSRI and tricyclic compounds. Neuropsychopharmacology. 2018 06; 43(7):1481-1491.
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Cruzat A, Hamrah P, Cavalcanti BM, Zheng L, Colby K, Pavan-Langston D. Corneal Reinnervation and Sensation Recovery in Patients With Herpes Zoster Ophthalmicus: An In Vivo and Ex Vivo Study of Corneal Nerves. Cornea. 2016 May; 35(5):619-25.
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Li W, Mukherjee A, Wu J, Zhang L, Teves ME, Li H, Nambiar S, Henderson SC, Horwitz AR, Strauss JF, Fang X, Zhang Z. Sperm Associated Antigen 6 (SPAG6) Regulates Fibroblast Cell Growth, Morphology, Migration and Ciliogenesis. Sci Rep. 2015 11 20; 5:16506.
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Oegema R, Cushion TD, Phelps IG, Chung SK, Dempsey JC, Collins S, Mullins JG, Dudding T, Gill H, Green AJ, Dobyns WB, Ishak GE, Rees MI, Doherty D. Recognizable cerebellar dysplasia associated with mutations in multiple tubulin genes. Hum Mol Genet. 2015 Sep 15; 24(18):5313-25.
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Kanojia D, Morshed RA, Zhang L, Miska JM, Qiao J, Kim JW, Pytel P, Balyasnikova IV, Lesniak MS, Ahmed AU. ßIII-Tubulin Regulates Breast Cancer Metastases to the Brain. . 2015 May; 14(5):1152-61.
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