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Pre-B Cell Receptors

"Pre-B Cell Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU IMMUNOGLOBULIN HEAVY CHAINS in complex with SURROGATE LIGHT CHAINS instead of conventional IMMUNOGLOBULIN LIGHT CHAINS. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the pre-B cell receptors is an important checkpoint in the development of mature B cells.


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This graph shows the total number of publications written about "Pre-B Cell Receptors" by people in this website by year, and whether "Pre-B Cell Receptors" was a major or minor topic of these publications.
Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 2003 and 2005 and 2013 and 2019
To see the data from this visualization as text, click here.