 In Situ Nick-End Labeling
"In Situ Nick-End Labeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
| Descriptor ID |
D020287
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| MeSH Number(s) |
E05.393.475
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| Concept/Terms |
In Situ Nick-End Labeling- In Situ Nick-End Labeling
- TUNEL
- Nick-End Labeling, In Situ
- In Situ Nick End Labelling
- In Situ Nick End Labeling
- In Situ Nick End-Labelling
- In Situ Nick-End Labelling
- Nick End-Labeling, In Situ
- Nick End Labeling, In Situ
- Nick End-Labelling, In Situ
- Nick End Labelling, In Situ
- Nick-End Labelling, In Situ
- In Situ Nick End-Labeling
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Below are MeSH descriptors whose meaning is more general than "In Situ Nick-End Labeling".
Below are MeSH descriptors whose meaning is more specific than "In Situ Nick-End Labeling".
This graph shows the total number of publications written about "In Situ Nick-End Labeling" by people in this website by year, and whether "In Situ Nick-End Labeling" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 12 | 12 | | 2002 | 0 | 10 | 10 | | 2003 | 0 | 9 | 9 | | 2004 | 0 | 6 | 6 | | 2005 | 0 | 6 | 6 | | 2006 | 0 | 10 | 10 | | 2007 | 0 | 3 | 3 | | 2008 | 1 | 6 | 7 | | 2009 | 0 | 3 | 3 | | 2010 | 0 | 5 | 5 | | 2011 | 0 | 3 | 3 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 4 | 4 | | 2014 | 0 | 5 | 5 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "In Situ Nick-End Labeling" by people in Profiles.
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Mathew B, Poston JN, Dreixler JC, Torres L, Lopez J, Zelkha R, Balyasnikova I, Lesniak MS, Roth S. Bone-marrow mesenchymal stem-cell administration significantly improves outcome after retinal ischemia in rats. Graefes Arch Clin Exp Ophthalmol. 2017 Aug; 255(8):1581-1592.
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Drobyshevsky A, Quinlan KA. Spinal cord injury in hypertonic newborns after antenatal hypoxia-ischemia in a rabbit model of cerebral palsy. Exp Neurol. 2017 07; 293:13-26.
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Roth S, Dreixler JC, Mathew B, Balyasnikova I, Mann JR, Boddapati V, Xue L, Lesniak MS. Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in Rats. Invest Ophthalmol Vis Sci. 2016 06 01; 57(7):3522-32.
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Huang H, Chen YM, Zhu F, Tang ST, Xiao JD, Li LL, Lin XJ. Down-regulated Na(+)/K(+)-ATPase activity in ischemic penumbra after focal cerebral ischemia/reperfusion in rats. Int J Clin Exp Pathol. 2015; 8(10):12708-17.
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Lauing KL, Cortes M, Domowicz MS, Henry JG, Baria AT, Schwartz NB. Aggrecan is required for growth plate cytoarchitecture and differentiation. Dev Biol. 2014 Dec 15; 396(2):224-36.
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Xu X, Philip JL, Razzaque MA, Lloyd JW, Muller CM, Akhter SA. High-molecular-weight polyethylene glycol inhibits myocardial ischemia-reperfusion injury in vivo. J Thorac Cardiovasc Surg. 2015 Feb; 149(2):588-93.
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Schoenfelder KP, Montague RA, Paramore SV, Lennox AL, Mahowald AP, Fox DT. Indispensable pre-mitotic endocycles promote aneuploidy in the Drosophila rectum. Development. 2014 Sep; 141(18):3551-60.
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Liu C, Karam R, Zhou Y, Su F, Ji Y, Li G, Xu G, Lu L, Wang C, Song M, Zhu J, Wang Y, Zhao Y, Foo WC, Zuo M, Valasek MA, Javle M, Wilkinson MF, Lu Y. The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma. Nat Med. 2014 Jun; 20(6):596-8.
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Dreixler JC, Poston JN, Balyasnikova I, Shaikh AR, Tupper KY, Conway S, Boddapati V, Marcet MM, Lesniak MS, Roth S. Delayed administration of bone marrow mesenchymal stem cell conditioned medium significantly improves outcome after retinal ischemia in rats. Invest Ophthalmol Vis Sci. 2014 Apr 03; 55(6):3785-96.
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MohanKumar K, Killingsworth CR, McIlwain RB, Timpa JG, Jagadeeswaran R, Namachivayam K, Kurundkar AR, Kelly DR, Garzon SA, Maheshwari A. Intestinal epithelial apoptosis initiates gut mucosal injury during extracorporeal membrane oxygenation in the newborn piglet. Lab Invest. 2014 Feb; 94(2):150-60.
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