Transcription Factor 7-Like 2 Protein
"Transcription Factor 7-Like 2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that takes part in WNT signaling pathway. The activity of the protein is regulated via its interaction with BETA CATENIN. Transcription factor 7-like 2 protein plays an important role in the embryogenesis of the PANCREAS and ISLET CELLS.
|Transcription Factor 7-Like 2 Protein
- Transcription Factor 7-Like 2 Protein
- Transcription Factor 7 Like 2 Protein
- T-Cell-Specific Transcription Factor 4
- T Cell Specific Transcription Factor 4
- T Cell Transcription Factor 4
- TCF7L2 Transcription Factor
- Transcription Factor, TCF7L2
- T Cell Factor 4
Below are MeSH descriptors whose meaning is more general than "Transcription Factor 7-Like 2 Protein".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor 7-Like 2 Protein".
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Below are the most recent publications written about "Transcription Factor 7-Like 2 Protein" by people in Profiles.
Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm. Am J Hum Genet. 2021 09 02; 108(9):1578-1589.
TCF7L2 (Transcription Factor 7-Like 2) Regulation of GATA6 (GATA-Binding Protein 6)-Dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia. Arterioscler Thromb Vasc Biol. 2019 02; 39(2):250-262.
Genetic Background Limits Generalizability of Genotype-Phenotype Relationships. Neuron. 2016 Sep 21; 91(6):1253-1259.
Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice. Hum Mol Genet. 2015 Mar 15; 24(6):1646-54.
TCF7L2 is a master regulator of insulin production and processing. Hum Mol Genet. 2014 Dec 15; 23(24):6419-31.
TCF7L2 and glucose metabolism: time to look beyond the pancreas. Diabetes. 2013 Mar; 62(3):706-8.
In vitro scan for enhancers at the TCF7L2 locus. Diabetologia. 2013 Jan; 56(1):121-5.
Association of fibrillin-3 and transcription factor-7-like 2 gene variants with metabolic phenotypes in PCOS. Obesity (Silver Spring). 2012 Jun; 20(6):1273-8.
Modulation ofTcf7l2 expression alters behavior in mice. PLoS One. 2011; 6(10):e26897.
Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism. Genome Res. 2011 Sep; 21(9):1417-25.