 Ligand-Gated Ion Channels
"Ligand-Gated Ion Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of ion channels that open or close in response to the binding of specific LIGANDS.
| Descriptor ID |
D058446
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| MeSH Number(s) |
D12.776.157.530.400.400 D12.776.543.550.425.500 D12.776.543.585.400.500
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| Concept/Terms |
Ligand-Gated Ion Channels- Ligand-Gated Ion Channels
- Ion Channels, Ligand-Gated
- Ligand Gated Ion Channels
- Ligand-Gated Channels
- Channels, Ligand-Gated
- Ligand Gated Channels
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Below are MeSH descriptors whose meaning is more general than "Ligand-Gated Ion Channels".
Below are MeSH descriptors whose meaning is more specific than "Ligand-Gated Ion Channels".
This graph shows the total number of publications written about "Ligand-Gated Ion Channels" by people in this website by year, and whether "Ligand-Gated Ion Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ligand-Gated Ion Channels" by people in Profiles.
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Kumar A, Basak S, Chakrapani S. Recombinant expression and purification of pentameric ligand-gated ion channels for Cryo-EM structural studies. Methods Enzymol. 2021; 652:81-103.
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Basak S, Schmandt N, Gicheru Y, Chakrapani S. Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel. Elife. 2017 03 06; 6.
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Basak S, Chatterjee S, Chakrapani S. Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels. J Vis Exp. 2016 07 04; (113).
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Schmandt N, Velisetty P, Chalamalasetti SV, Stein RA, Bonner R, Talley L, Parker MD, Mchaourab HS, Yee VC, Lodowski DT, Chakrapani S. A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation. J Gen Physiol. 2015 Oct; 146(4):323-40.
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Chakrapani S. EPR Studies of Gating Mechanisms in Ion Channels. Methods Enzymol. 2015; 557:279-306.
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Velisetty P, Chalamalasetti SV, Chakrapani S. Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC). J Biol Chem. 2014 Jan 31; 289(5):3013-25.
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Velisetty P, Chalamalasetti SV, Chakrapani S. Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC). J Biol Chem. 2012 Oct 26; 287(44):36864-72.
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