Cryptochromes
"Cryptochromes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Flavoproteins that function as circadian rhythm signaling proteins in ANIMALS and as blue-light photoreceptors in PLANTS. They are structurally-related to DNA PHOTOLYASES and it is believed that both classes of proteins may have originated from an earlier protein that played a role in protecting primitive organisms from the cyclical exposure to UV LIGHT.
Descriptor ID |
D056931
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MeSH Number(s) |
D12.644.128.150 D12.776.189.250 D12.776.331.180 D12.776.765.593.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cryptochromes".
Below are MeSH descriptors whose meaning is more specific than "Cryptochromes".
This graph shows the total number of publications written about "Cryptochromes" by people in this website by year, and whether "Cryptochromes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2003 | 0 | 2 | 2 | 2004 | 0 | 1 | 1 | 2008 | 0 | 2 | 2 | 2011 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cryptochromes" by people in Profiles.
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Berntsson O, Rodriguez R, Henry L, Panman MR, Hughes AJ, Einholz C, Weber S, Ihalainen JA, Henning R, Kosheleva I, Schleicher E, Westenhoff S. Photoactivation of Drosophila melanogaster cryptochrome through sequential conformational transitions. Sci Adv. 2019 07; 5(7):eaaw1531.
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Annayev Y, Adar S, Chiou YY, Lieb JD, Sancar A, Ye R. Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression. J Biol Chem. 2014 Feb 21; 289(8):5013-24.
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Herrou J, Crosson S. Function, structure and mechanism of bacterial photosensory LOV proteins. Nat Rev Microbiol. 2011 Aug 08; 9(10):713-23.
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Lee J, Natarajan M, Nashine VC, Socolich M, Vo T, Russ WP, Benkovic SJ, Ranganathan R. Surface sites for engineering allosteric control in proteins. Science. 2008 Oct 17; 322(5900):438-42.
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Strickland D, Moffat K, Sosnick TR. Light-activated DNA binding in a designed allosteric protein. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10709-14.
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Kennis JT, van Stokkum IH, Crosson S, Gauden M, Moffat K, van Grondelle R. The LOV2 domain of phototropin: a reversible photochromic switch. J Am Chem Soc. 2004 Apr 14; 126(14):4512-3.
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Kennis JT, Crosson S, Gauden M, van Stokkum IH, Moffat K, van Grondelle R. Primary reactions of the LOV2 domain of phototropin, a plant blue-light photoreceptor. Biochemistry. 2003 Apr 01; 42(12):3385-92.
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Crosson S, Rajagopal S, Moffat K. The LOV domain family: photoresponsive signaling modules coupled to diverse output domains. Biochemistry. 2003 Jan 14; 42(1):2-10.
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Crosson S, Moffat K. Photoexcited structure of a plant photoreceptor domain reveals a light-driven molecular switch. Plant Cell. 2002 May; 14(5):1067-75.
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Crosson S, Moffat K. Structure of a flavin-binding plant photoreceptor domain: insights into light-mediated signal transduction. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):2995-3000.
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