Heterogeneous-Nuclear Ribonucleoproteins
"Heterogeneous-Nuclear Ribonucleoproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of ribonucleoproteins that were originally found as proteins bound to nascent RNA transcripts in the form of ribonucleoprotein particles. Although considered ribonucleoproteins they are primarily classified by their protein component. They are involved in a variety of processes such as packaging of RNA and RNA TRANSPORT within the nucleus. A subset of heterogeneous-nuclear ribonucleoproteins are involved in additional functions such as nucleocytoplasmic transport (ACTIVE TRANSPORT, CELL NUCLEUS) of RNA and mRNA stability in the CYTOPLASM.
| Descriptor ID |
D034441
|
| MeSH Number(s) |
D12.776.157.725.813.750 D12.776.664.962.813.750
|
| Concept/Terms |
Heterogeneous-Nuclear Ribonucleoproteins- Heterogeneous-Nuclear Ribonucleoproteins
- Heterogeneous Nuclear Ribonucleoproteins
- Ribonucleoproteins, Heterogeneous-Nuclear
- hnRNP
- Informofer
- Heterogeneous Nuclear Ribonucleoprotein
- Nuclear Ribonucleoprotein, Heterogeneous
- Ribonucleoprotein, Heterogeneous Nuclear
|
Below are MeSH descriptors whose meaning is more general than "Heterogeneous-Nuclear Ribonucleoproteins".
Below are MeSH descriptors whose meaning is more specific than "Heterogeneous-Nuclear Ribonucleoproteins".
This graph shows the total number of publications written about "Heterogeneous-Nuclear Ribonucleoproteins" by people in this website by year, and whether "Heterogeneous-Nuclear Ribonucleoproteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterogeneous-Nuclear Ribonucleoproteins" by people in Profiles.
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Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing. Neuron. 2023 05 17; 111(10):1637-1650.e5.
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Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019 10 03; 76(1):70-81.e9.
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Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension. Circulation. 2017 12 19; 136(25):2486-2490.
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N6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein. Nucleic Acids Res. 2017 Jun 02; 45(10):6051-6063.
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Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Cell. 2016 Aug 25; 166(5):1147-1162.e15.
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Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity. PLoS Genet. 2015 Dec; 11(12):e1005713.
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RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts. Genome Res. 2015 Jan; 25(1):1-13.
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Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study. BMC Med Genomics. 2014; 7 Suppl 1:S1.
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Role of the lncRNA-p53 regulatory network in cancer. J Mol Cell Biol. 2014 Jun; 6(3):181-91.
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Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts. Haematologica. 2014 Jun; 99(6):1032-40.