"RNA-Binding Protein EWS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.
| Descriptor ID |
D034802
|
| MeSH Number(s) |
D12.644.360.650 D12.776.157.142.750 D12.776.157.725.813.750.900 D12.776.476.650 D12.776.624.664.700.913 D12.776.664.962.813.750.900
|
| Concept/Terms |
RNA-Binding Protein EWS- RNA-Binding Protein EWS
- EWS, RNA-Binding Protein
- RNA Binding Protein EWS
- EWSR1 Protein
- Protein, EWSR1
- Ewing Sarcoma Breakpoint Region 1 Protein
- EWS Proto-Oncogene Protein
- EWS Proto Oncogene Protein
- Proto-Oncogene Protein, EWS
- Ewing Sarcoma Breakpointregion 1 Protein
- EWS RNA Binding Protein 1
- EWS Protein
|
Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein EWS".
Below are MeSH descriptors whose meaning is more specific than "RNA-Binding Protein EWS".
This graph shows the total number of publications written about "RNA-Binding Protein EWS" by people in this website by year, and whether "RNA-Binding Protein EWS" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "RNA-Binding Protein EWS" by people in Profiles.
-
Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma. Cancer Lett. 2023 01 01; 552:215984.
-
Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility. Cell Rep. 2018 02 06; 22(6):1473-1483.
-
Malignant round cell tumor of bone with EWSR1-NFATC2 gene fusion. Virchows Arch. 2014 Aug; 465(2):233-9.
-
EWSR1 binds the hepatitis C virus cis-acting replication element and is required for efficient viral replication. J Virol. 2013 Jun; 87(12):6625-34.
-
Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription. Genome Res. 2012 Feb; 22(2):259-70.
-
Angiomatoid fibrous histiocytoma: pleomorphic variant associated with multiplication of EWSR1-CREB1 fusion gene. Pathol Oncol Res. 2012 Apr; 18(2):545-8.
-
Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors. Cancer Biol Ther. 2005 Apr; 4(4):449-55.
-
Induction of tenascin-C by tumor-specific EWS-ETS fusion genes. Genes Chromosomes Cancer. 2003 Mar; 36(3):224-32.
-
The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors. Oncogene. 2002 Nov 28; 21(54):8302-9.