 Lectins
"Lectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.
| Descriptor ID |
D037102
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| MeSH Number(s) |
D12.776.503
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lectins".
Below are MeSH descriptors whose meaning is more specific than "Lectins".
This graph shows the total number of publications written about "Lectins" by people in this website by year, and whether "Lectins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 3 | 1 | 4 | | 1982 | 1 | 1 | 2 | | 1986 | 0 | 1 | 1 | | 1988 | 2 | 1 | 3 | | 1989 | 1 | 0 | 1 | | 1991 | 1 | 1 | 2 | | 1992 | 0 | 1 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 1 | 1 | 2 | | 1996 | 1 | 1 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 1 | 1 | 2 | | 2000 | 3 | 1 | 4 | | 2002 | 1 | 1 | 2 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 2 | 1 | 3 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 2 | 2 | | 2009 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lectins" by people in Profiles.
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Fettis MM, Hudalla GA. Engineering Reactive Oxygen Species-Resistant Galectin-1 Dimers with Enhanced Lectin Activity. Bioconjug Chem. 2018 07 18; 29(7):2489-2496.
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Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ. Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils. Science. 2017 12 01; 358(6367).
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Chen NT, Souris JS, Cheng SH, Chu CH, Wang YC, Konda V, Dougherty U, Bissonnette M, Mou CY, Chen CT, Lo LW. Lectin-functionalized mesoporous silica nanoparticles for endoscopic detection of premalignant colonic lesions. Nanomedicine. 2017 Aug; 13(6):1941-1952.
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Krishnan BP, Raghu S, Mukherjee S, Sureshan KM. Organogel-assisted topochemical synthesis of multivalent glyco-polymer for high-affinity lectin binding. Chem Commun (Camb). 2016 Dec 01; 52(98):14089-14092.
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Ghosh SK, Weinberg A. When Mr. Fap Meets the Gals. Cell Host Microbe. 2016 08 10; 20(2):125-6.
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Kulkarni HS, Guzy RD, McEvoy C. YKL-40 in pediatric asthma, MUC5B promoter polymorphism in idiopathic pulmonary fibrosis, and esmolol in septic shock. Am J Respir Crit Care Med. 2014 May 01; 189(9):1138-40.
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Shakhsheer B, Anderson M, Khatib K, Tadoori L, Joshi L, Lisacek F, Hirschman L, Mullen E. SugarBind database (SugarBindDB): a resource of pathogen lectins and corresponding glycan targets. J Mol Recognit. 2013 Sep; 26(9):426-31.
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Kamada Y, Kinoshita N, Tsuchiya Y, Kobayashi K, Fujii H, Terao N, Kamihagi K, Koyama N, Yamada S, Daigo Y, Nakamura Y, Taniguchi N, Miyoshi E. Reevaluation of a lectin antibody ELISA kit for measuring fucosylated haptoglobin in various conditions. Clin Chim Acta. 2013 Feb 18; 417:48-53.
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Babrowski T, Holbrook C, Moss J, Gottlieb L, Valuckaite V, Zaborin A, Poroyko V, Liu DC, Zaborina O, Alverdy JC. Pseudomonas aeruginosa virulence expression is directly activated by morphine and is capable of causing lethal gut-derived sepsis in mice during chronic morphine administration. Ann Surg. 2012 Feb; 255(2):386-93.
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Chen CC, Pekow J, Llado V, Kanneganti M, Lau CW, Mizoguchi A, Mino-Kenudson M, Bissonnette M, Mizoguchi E. Chitinase 3-like-1 expression in colonic epithelial cells as a potentially novel marker for colitis-associated neoplasia. Am J Pathol. 2011 Sep; 179(3):1494-503.
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