"LIM Domain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large class of structurally-related proteins that contain one or more LIM zinc finger domains. Many of the proteins in this class are involved in intracellular signaling processes and mediate their effects via LIM domain protein-protein interactions. The name LIM is derived from the first three proteins in which the motif was found: LIN-11, Isl1 and Mec-3.
| Descriptor ID |
D060588
|
| MeSH Number(s) |
D12.776.512
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "LIM Domain Proteins".
Below are MeSH descriptors whose meaning is more specific than "LIM Domain Proteins".
This graph shows the total number of publications written about "LIM Domain Proteins" by people in this website by year, and whether "LIM Domain Proteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "LIM Domain Proteins" by people in Profiles.
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Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain. Elife. 2023 06 09; 12.
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LIM domain proteins in cell mechanobiology. Cytoskeleton (Hoboken). 2021 06; 78(6):303-311.
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Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25532-25542.
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Prickle1 is required for EMT and migration of zebrafish cranial neural crest. Dev Biol. 2019 04 01; 448(1):16-35.
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Chromosomes come together to help mice distinguish odours. Nature. 2019 01; 565(7740):439-440.
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Pdlim7 Regulates Arf6-Dependent Actin Dynamics and Is Required for Platelet-Mediated Thrombosis in Mice. PLoS One. 2016; 11(10):e0164042.
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The utility of IgM, CD21, HGAL and LMO2 in the diagnosis of pediatric follicular lymphoma. Hum Pathol. 2015 Apr; 46(4):629-33.
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LMO7-null mice exhibit phenotypes consistent with emery-dreifuss muscular dystrophy. Muscle Nerve. 2015 Feb; 51(2):222-8.
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Targeted analysis of whole genome sequence data to diagnose genetic cardiomyopathy. Circ Cardiovasc Genet. 2014 Dec; 7(6):751-759.
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Emerin in health and disease. Semin Cell Dev Biol. 2014 May; 29:95-106.