"Wnt Signaling Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, and the vertebrate INT gene. The signaling pathway is initiated by the binding of WNT PROTEINS to cell surface WNT RECEPTORS which interact with the AXIN SIGNALING COMPLEX and an array of second messengers that influence the actions of BETA CATENIN.
| Descriptor ID |
D060449
|
| MeSH Number(s) |
G02.111.820.925 G04.835.925
|
| Concept/Terms |
Wnt Signaling Pathway- Wnt Signaling Pathway
- Pathway, Wnt Signaling
- Pathways, Wnt Signaling
- Signaling Pathway, Wnt
- Signaling Pathways, Wnt
- Wnt Signaling Pathways
- Wnt Pathway
- Pathway, Wnt
- Pathways, Wnt
- Wnt Pathways
Wnt beta-Catenin Signaling Pathway- Wnt beta-Catenin Signaling Pathway
- Wnt beta Catenin Signaling Pathway
- Wnt Pathway, Canonical
- Canonical Wnt Pathway
- Canonical Wnt Pathways
- Pathway, Canonical Wnt
- Pathways, Canonical Wnt
- Wnt Pathways, Canonical
|
Below are MeSH descriptors whose meaning is more general than "Wnt Signaling Pathway".
Below are MeSH descriptors whose meaning is more specific than "Wnt Signaling Pathway".
This graph shows the total number of publications written about "Wnt Signaling Pathway" by people in this website by year, and whether "Wnt Signaling Pathway" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 3 | 3 |
| 2013 | 6 | 6 | 12 |
| 2014 | 2 | 2 | 4 |
| 2015 | 2 | 2 | 4 |
| 2016 | 1 | 3 | 4 |
| 2017 | 4 | 2 | 6 |
| 2018 | 3 | 3 | 6 |
| 2019 | 2 | 3 | 5 |
| 2020 | 4 | 4 | 8 |
| 2021 | 3 | 3 | 6 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 3 | 3 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Wnt Signaling Pathway" by people in Profiles.
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A genome-wide association meta-analysis links hidradenitis suppurativa to common and rare sequence variants causing disruption of the Notch and Wnt/ß-catenin signaling pathways. J Am Acad Dermatol. 2025 Apr; 92(4):761-772.
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Wnt/ß-catenin maintains epithelial IL-33 in the colonic stem and progenitor cell niche and drives its induction in colitis. Mucosal Immunol. 2025 Feb; 18(1):248-256.
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Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS Chem Biol. 2024 02 16; 19(2):300-307.
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Reversal of Lactate and PD-1-mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer. Clin Cancer Res. 2023 05 15; 29(10):1952-1968.
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EZH2 activates Wnt/ß-catenin signaling in human uterine fibroids, which is inhibited by the natural compound methyl jasmonate. F S Sci. 2023 08; 4(3):239-256.
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Ectodermal Wnt signaling, cell fate determination, and polarity of the skate gill arch skeleton. Elife. 2023 03 20; 12.
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Pyrvinium doubles against WNT-driven cancer. J Biol Chem. 2022 10; 298(10):102479.
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TCF-1: a maverick in T cell development and function. Nat Immunol. 2022 05; 23(5):671-678.
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Regulation of stem cell identity by miR-200a during spinal cord regeneration. Development. 2022 02 01; 149(3).
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The Tight Junction Protein ZO-1 Is Dispensable for Barrier Function but Critical for Effective Mucosal Repair. Gastroenterology. 2021 12; 161(6):1924-1939.