"ADAMTS Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins, which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the EXTRACELLULAR MATRIX.
| Descriptor ID |
D000071096
|
| MeSH Number(s) |
D08.811.277.656.675.374.102.500 D09.400.430.500.500 D12.776.395.033.500 D12.776.860.300.085
|
| Concept/Terms |
ADAMTS Proteins- ADAMTS Proteins
- Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins
- A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins
- ADAMTS Proteases
|
Below are MeSH descriptors whose meaning is more general than "ADAMTS Proteins".
Below are MeSH descriptors whose meaning is more specific than "ADAMTS Proteins".
This graph shows the total number of publications written about "ADAMTS Proteins" by people in this website by year, and whether "ADAMTS Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "ADAMTS Proteins" by people in Profiles.
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Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours. Br J Cancer. 2006 Apr 24; 94(8):1186-93.