Glycogen Synthase Kinase 3 beta
"Glycogen Synthase Kinase 3 beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.
| Descriptor ID |
D000071679
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| MeSH Number(s) |
D05.500.117.875.500 D08.811.913.696.620.682.700.429.500.500 D08.811.913.696.620.682.700.646.625.500 D12.644.360.300.500.500 D12.776.476.081.875.500 D12.776.476.300.500.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3 beta".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3 beta".
This graph shows the total number of publications written about "Glycogen Synthase Kinase 3 beta" by people in this website by year, and whether "Glycogen Synthase Kinase 3 beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 5 | 5 |
| 2012 | 0 | 4 | 4 |
| 2013 | 0 | 5 | 5 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 3 | 3 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glycogen Synthase Kinase 3 beta" by people in Profiles.
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Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3ß-mediated restriction of epithelial IL-33. Nat Commun. 2021 02 05; 12(1):836.
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Telocinobufagin, a Novel Cardiotonic Steroid, Promotes Renal Fibrosis via Na?/K?-ATPase Profibrotic Signaling Pathways. Int J Mol Sci. 2018 Aug 29; 19(9).
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Leptin in the nucleus accumbens core disrupts acute cocaine effects: Implications for GSK3ß connections. Behav Brain Res. 2018 Jan 30; 337:46-52.
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POMC maintains tumor-initiating properties of tumor tissue-derived long-term-cultured breast cancer stem cells. Int J Cancer. 2017 06 01; 140(11):2517-2525.
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GSK-3 inhibition overcomes chemoresistance in human breast cancer. Cancer Lett. 2016 10 01; 380(2):384-392.
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SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3ß. Mol Cell Biol. 2015 Dec 14; 36(5):678-92.
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Cardioprotective Signature of Short-Term Caloric Restriction. PLoS One. 2015; 10(6):e0130658.
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Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity. J Clin Invest. 2015 May; 125(5):2109-22.
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Exogenous activation of Wnt/ß-catenin signaling attenuates binge alcohol-induced deficient bone fracture healing. Alcohol Alcohol. 2014 Jul-Aug; 49(4):399-408.
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Baicalein protects cardiomyocytes against mitochondrial oxidant injury associated with JNK inhibition and mitochondrial Akt activation. Am J Chin Med. 2014; 42(1):79-94.