Glycogen Synthase Kinase 3 beta
"Glycogen Synthase Kinase 3 beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.
Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3 beta".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3 beta".
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Below are the most recent publications written about "Glycogen Synthase Kinase 3 beta" by people in Profiles.
Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3?-mediated restriction of epithelial IL-33. Nat Commun. 2021 02 05; 12(1):836.
Telocinobufagin, a Novel Cardiotonic Steroid, Promotes Renal Fibrosis via Na?/K?-ATPase Profibrotic Signaling Pathways. Int J Mol Sci. 2018 Aug 29; 19(9).
Leptin in the nucleus accumbens core disrupts acute cocaine effects: Implications for GSK3? connections. Behav Brain Res. 2018 Jan 30; 337:46-52.
GSK-3 inhibition overcomes chemoresistance in human breast cancer. Cancer Lett. 2016 10 01; 380(2):384-392.
SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3?. Mol Cell Biol. 2015 Dec 14; 36(5):678-92.
Cardioprotective Signature of Short-Term Caloric Restriction. PLoS One. 2015; 10(6):e0130658.
Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity. J Clin Invest. 2015 May; 125(5):2109-22.
Exogenous activation of Wnt/?-catenin signaling attenuates binge alcohol-induced deficient bone fracture healing. Alcohol Alcohol. 2014 Jul-Aug; 49(4):399-408.
Baicalein protects cardiomyocytes against mitochondrial oxidant injury associated with JNK inhibition and mitochondrial Akt activation. Am J Chin Med. 2014; 42(1):79-94.
Destabilization of heterologous proteins mediated by the GSK3? phosphorylation domain of the ?-catenin protein. Cell Physiol Biochem. 2013; 32(5):1187-99.