"Jagged-2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serrate-jagged protein that functions to modulate signal transduction from NOTCH RECEPTORS in CELL DIFFERENTIATION. It may also regulate the expression of CYTOKINES.
| Descriptor ID |
D000072101
|
| MeSH Number(s) |
D12.644.276.930.750 D12.776.157.125.797.750 D12.776.543.800.750 D23.529.930.750
|
| Concept/Terms |
Jagged-2 Protein- Jagged-2 Protein
- Jagged 2 Protein
- Serrate2 Protein
- Serrate-2 Protein
- Serrate 2 Protein
- Jagged2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Jagged-2 Protein".
Below are MeSH descriptors whose meaning is more specific than "Jagged-2 Protein".
This graph shows the total number of publications written about "Jagged-2 Protein" by people in this website by year, and whether "Jagged-2 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Jagged-2 Protein" by people in Profiles.
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Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis. Nature. 2016 06 30; 534(7609):700-4.
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Spatial segregation of gamma-secretase and substrates in distinct membrane domains. J Biol Chem. 2005 Jul 08; 280(27):25892-900.
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The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage. J Biol Chem. 2003 Mar 07; 278(10):7751-4.
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The p53 family member genes are involved in the Notch signal pathway. J Biol Chem. 2002 Jan 04; 277(1):719-24.
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Requirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1. J Mol Neurosci. 2000 Dec; 15(3):189-204.