"Superoxide Dismutase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.
- Superoxide Dismutase-1
- Cuprozinc Superoxide Dismutase
- Superoxide Dismutase, Cuprozinc
- Superoxide Dismutase 1
- Cu-Zn Superoxide Dismutase
- Cu Zn Superoxide Dismutase
- Superoxide Dismutase, Cu-Zn
- SOD-1 Protein
- SOD 1 Protein
- SOD1 Protein
Below are MeSH descriptors whose meaning is more general than "Superoxide Dismutase-1".
Below are MeSH descriptors whose meaning is more specific than "Superoxide Dismutase-1".
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Below are the most recent publications written about "Superoxide Dismutase-1" by people in Profiles.
Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS. Neurobiol Dis. 2020 03; 136:104702.
The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS. Neurobiol Dis. 2019 07; 127:527-544.
Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction. World J Gastroenterol. 2018 Apr 28; 24(16):1748-1765.
Poloxamer 188 decreases membrane toxicity of mutant SOD1 and ameliorates pathology observed in SOD1 mouse model for ALS. Neurobiol Dis. 2018 07; 115:115-126.
Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregates. Cell Death Dis. 2018 03 14; 9(3):407.
AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species. Cell Rep. 2017 Oct 03; 21(1):1-9.
S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects. Sci Rep. 2017 01 25; 7:41141.
Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia. J Physiol. 2017 01 01; 595(1):63-77.
MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell. Free Radic Biol Med. 2016 12; 101:32-43.
12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets. Mol Cell Biol. 2014 Oct 01; 34(19):3735-45.