"Splicing Factor U2AF" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RNA splicing factor that performs a critical function in both constitutive and enhancer-dependent RNA SPLICING. It recruits RIBONUCLEOPROTEIN, U2 SMALL NUCLEAR to the splice site and mediates interactions between it, the RNA molecule, and other splicing factors for accurate 3'-splice site selection.
Descriptor ID |
D000072668
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MeSH Number(s) |
D12.776.157.725.829.750 D12.776.664.962.829.750
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Concept/Terms |
Splicing Factor U2AF- Splicing Factor U2AF
- Factor U2AF, Splicing
- U2AF, Splicing Factor
- U2AF 65
- U2AF(65)
- U2AF Splicing Factor
- Factor, U2AF Splicing
- Splicing Factor, U2AF
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Below are MeSH descriptors whose meaning is more general than "Splicing Factor U2AF".
Below are MeSH descriptors whose meaning is more specific than "Splicing Factor U2AF".
This graph shows the total number of publications written about "Splicing Factor U2AF" by people in this website by year, and whether "Splicing Factor U2AF" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "Splicing Factor U2AF" by people in Profiles.
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Frequency of MAP2K1, TP53, and U2AF1 Mutations in BRAF-mutated Langerhans Cell Histiocytosis: Further Characterizing the Genomic Landscape of LCH. Am J Surg Pathol. 2018 07; 42(7):885-890.
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Mutations in DNMT3A, U2AF1, and EZH2 identify intermediate-risk acute myeloid leukemia patients with poor outcome after CR1. Blood Cancer J. 2018 01 10; 8(1):4.
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Next-generation sequencing of acute myeloid leukemia identifies the significance of TP53, U2AF1, ASXL1, and TET2 mutations. Mod Pathol. 2015 May; 28(5):706-14.
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Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast. Genes Dev. 2013 Mar 15; 27(6):627-38.
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Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Blood. 2009 Nov 05; 114(19):4233-42.