Tumor Suppressor Protein p53
"Tumor Suppressor Protein p53" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
| Descriptor ID |
D016159
|
| MeSH Number(s) |
D12.776.157.687.650 D12.776.260.820 D12.776.624.776.775 D12.776.660.720.650 D12.776.744.845
|
| Concept/Terms |
Tumor Suppressor Protein p53- Tumor Suppressor Protein p53
- p53 Antigen
- TP53 Protein
- TRP53 Protein
- p53 Tumor Suppressor Protein
- pp53 Phosphoprotein
- Phosphoprotein, pp53
- Cellular Tumor Antigen p53
- Oncoprotein p53
|
Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor Protein p53".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor Protein p53".
This graph shows the total number of publications written about "Tumor Suppressor Protein p53" by people in this website by year, and whether "Tumor Suppressor Protein p53" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 2 | 3 | 5 |
| 1996 | 3 | 4 | 7 |
| 1997 | 2 | 3 | 5 |
| 1998 | 3 | 5 | 8 |
| 1999 | 1 | 1 | 2 |
| 2000 | 3 | 4 | 7 |
| 2001 | 4 | 2 | 6 |
| 2002 | 9 | 9 | 18 |
| 2003 | 7 | 3 | 10 |
| 2004 | 9 | 2 | 11 |
| 2005 | 6 | 4 | 10 |
| 2006 | 8 | 5 | 13 |
| 2007 | 3 | 7 | 10 |
| 2008 | 5 | 11 | 16 |
| 2009 | 3 | 2 | 5 |
| 2010 | 11 | 5 | 16 |
| 2011 | 9 | 9 | 18 |
| 2012 | 5 | 7 | 12 |
| 2013 | 5 | 1 | 6 |
| 2014 | 8 | 5 | 13 |
| 2015 | 7 | 6 | 13 |
| 2016 | 6 | 5 | 11 |
| 2017 | 8 | 4 | 12 |
| 2018 | 5 | 7 | 12 |
| 2019 | 7 | 7 | 14 |
| 2020 | 5 | 3 | 8 |
| 2021 | 5 | 3 | 8 |
| 2022 | 4 | 6 | 10 |
| 2023 | 2 | 9 | 11 |
| 2024 | 4 | 5 | 9 |
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Below are the most recent publications written about "Tumor Suppressor Protein p53" by people in Profiles.
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Prognostic impact of 'multi-hit' versus 'single-hit' TP53 alteration in patients with acute myeloid leukemia: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases. Haematologica. 2024 11 01; 109(11):3533-3542.
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IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 Aug 28; 15(1):7421.
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Comprehensive molecular characterization of early stage grade 3 endometrioid endometrial adenocarcinoma. Gynecol Oncol. 2024 Oct; 189:138-145.
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Cell free DNA in patients with pancreatic adenocarcinoma: clinicopathologic correlations. Sci Rep. 2024 07 08; 14(1):15744.
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Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study. Cancer Res Commun. 2024 Jun 27; 4(6):1597-1608.
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Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms. Blood Cancer J. 2024 06 18; 14(1):99.
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Comparing venetoclax in combination with hypomethylating agents to hypomethylating agent-based therapies for treatment naive TP53-mutated acute myeloid leukemia: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND). Blood Cancer J. 2024 02 20; 14(1):32.
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Utility or futility? A contemporary approach to allogeneic hematopoietic cell transplantation for TP53-mutated MDS/AML. Blood Adv. 2024 02 13; 8(3):553-561.
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Lung adenocarcinomas with isolated TP53 mutation: A comprehensive clinical, cytopathologic and molecular characterization. Cancer Med. 2024 Jan; 13(1):e6873.
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TP53 variant allele frequency and therapy-related setting independently predict survival in myelodysplastic syndromes with del(5q). Br J Haematol. 2024 Apr; 204(4):1243-1248.