NAV1.1 Voltage-Gated Sodium Channel
"NAV1.1 Voltage-Gated Sodium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A voltage-gated sodium channel subtype that is predominantly expressed in the CENTRAL NERVOUS SYSTEM. Defects in the SCN1A gene which codes for the alpha subunit of this sodium channel are associated with DRAVET SYNDROME, generalized epilepsy with febrile seizures plus, type 2 (GEFS+2), and familial hemiplegic migraine type 3.
| Descriptor ID |
D062550
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| MeSH Number(s) |
D12.776.157.530.400.875.750.100 D12.776.543.550.450.875.750.100 D12.776.543.585.400.875.750.100 D12.776.631.960.100
|
| Concept/Terms |
NAV1.1 Voltage-Gated Sodium Channel- NAV1.1 Voltage-Gated Sodium Channel
- NAV1.1 Voltage Gated Sodium Channel
- Voltage-Gated Sodium Channel Type 1
- Voltage Gated Sodium Channel Type 1
- Type 1 Voltage-Gated Sodium Channel
- Type 1 Voltage Gated Sodium Channel
Voltage-Gated Sodium Channel Type 1 Subunit alpha- Voltage-Gated Sodium Channel Type 1 Subunit alpha
- Voltage Gated Sodium Channel Type 1 Subunit alpha
- Sodium Channel, Voltage-Gated, Type I, alpha Protein
- SCN1A Sodium Channel alpha Subunit
- Voltage-Gated Sodium Channel Type 1 alpha Subunit
- Voltage Gated Sodium Channel Type 1 alpha Subunit
- NAV1.1 alpha Subunit
- alpha Subunit, NAV1.1
|
Below are MeSH descriptors whose meaning is more general than "NAV1.1 Voltage-Gated Sodium Channel".
Below are MeSH descriptors whose meaning is more specific than "NAV1.1 Voltage-Gated Sodium Channel".
This graph shows the total number of publications written about "NAV1.1 Voltage-Gated Sodium Channel" by people in this website by year, and whether "NAV1.1 Voltage-Gated Sodium Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "NAV1.1 Voltage-Gated Sodium Channel" by people in Profiles.
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Core Features Differentiate Dravet Syndrome from Febrile Seizures. J Pediatr. 2023 07; 258:113416.
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Severe peri-ictal respiratory dysfunction is common in Dravet syndrome. J Clin Invest. 2018 03 01; 128(3):1141-1153.
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Ictal ontogeny in Dravet syndrome. Clin Neurophysiol. 2015 Mar; 126(3):446-55.
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Molecular microdomains in a sensory terminal, the vestibular calyx ending. J Neurosci. 2011 Jul 06; 31(27):10101-14.
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Child Neurology: Dravet syndrome: when to suspect the diagnosis. Neurology. 2009 Sep 29; 73(13):e59-62.
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Dravet syndrome (severe myoclonic epilepsy in infancy): a retrospective study of 16 patients. J Child Neurol. 2007 Feb; 22(2):185-94.