Cyclic GMP-Dependent Protein Kinase Type I
"Cyclic GMP-Dependent Protein Kinase Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to alternative splicing of its mRNA.
| Descriptor ID |
D062965
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| MeSH Number(s) |
D08.811.913.696.620.682.700.150.150.500 D12.644.360.200.150.500 D12.776.476.200.150.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclic GMP-Dependent Protein Kinase Type I".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP-Dependent Protein Kinase Type I".
This graph shows the total number of publications written about "Cyclic GMP-Dependent Protein Kinase Type I" by people in this website by year, and whether "Cyclic GMP-Dependent Protein Kinase Type I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclic GMP-Dependent Protein Kinase Type I" by people in Profiles.
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Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus. Genes Immun. 2015 Jan-Feb; 16(1):15-23.
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Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells. Antioxid Redox Signal. 2012 Aug 01; 17(3):460-70.
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Activation of cGMP-dependent protein kinase by protein kinase C. J Biol Chem. 2003 May 09; 278(19):16706-12.