"RGS Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of evolutionarily conserved proteins that function as negative regulators of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it to revert to its inactive (GDP-bound) form.
| Descriptor ID |
D020710
|
| MeSH Number(s) |
D12.644.360.325.150.750 D12.776.476.325.150.750
|
| Concept/Terms |
RGS Proteins- RGS Proteins
- Regulators of G-Protein Signaling Proteins
- Regulators of G Protein Signaling Proteins
- RGS Protein (G-Protein Signaling)
|
Below are MeSH descriptors whose meaning is more general than "RGS Proteins".
Below are MeSH descriptors whose meaning is more specific than "RGS Proteins".
This graph shows the total number of publications written about "RGS Proteins" by people in this website by year, and whether "RGS Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 1 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "RGS Proteins" by people in Profiles.
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Genome sequencing unveils a regulatory landscape of platelet reactivity. Nat Commun. 2021 Jun 15; 12(1):3626.
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Regulator of G-Protein Signaling 5 Maintains Brain Endothelial Cell Function in Focal Cerebral Ischemia. J Am Heart Assoc. 2020 09 15; 9(18):e017533.
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Ethanol Disinhibits Dorsolateral Striatal Medium Spiny Neurons Through Activation of A Presynaptic Delta Opioid Receptor. Neuropsychopharmacology. 2016 06; 41(7):1831-40.
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RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 15; 305(10):L693-701.
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Voltage drives diverse endocannabinoid signals to mediate striatal microcircuit-specific plasticity. Nat Neurosci. 2013 Sep; 16(9):1275-83.
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Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli. Nat Biotechnol. 2013 Apr; 31(4):342-9.
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RGS expression in cancer: oncomining the cancer microarray data. J Recept Signal Transduct Res. 2013 Jun; 33(3):166-71.
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A finer tuning of G-protein signaling through regulated control of RGS proteins. Am J Physiol Heart Circ Physiol. 2012 Jul; 303(1):H19-35.
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Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart. Sci Transl Med. 2011 Sep 14; 3(100):100ra88.
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Priming with very low-affinity peptide ligands gives rise to CD8(+) T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)ß-mediated suppression. Cancer Immunol Immunother. 2011 Nov; 60(11):1543-51.