"Aurora Kinase B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An aurora kinase that is a component of the chromosomal passenger protein complex and is involved in the regulation of MITOSIS. It mediates proper CHROMOSOME SEGREGATION and contractile ring function during CYTOKINESIS.
|Aurora Kinase B
- Aurora Kinase B
- Serine-Threonine Protein Kinase 12
- Serine Threonine Protein Kinase 12
- Aurora-Related Kinase 2
- Aurora Related Kinase 2
- Aurora B Kinases
- Aurora Kinases B
Below are MeSH descriptors whose meaning is more general than "Aurora Kinase B".
Below are MeSH descriptors whose meaning is more specific than "Aurora Kinase B".
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Below are the most recent publications written about "Aurora Kinase B" by people in Profiles.
Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins. J Mol Biol. 2022 06 30; 434(12):167602.
Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence. J Cell Sci. 2019 07 01; 132(13).
Allosteric modulation of a human protein kinase with monobodies. Proc Natl Acad Sci U S A. 2019 07 09; 116(28):13937-13942.
PLK1 plays dual roles in centralspindlin regulation during cytokinesis. J Cell Biol. 2019 04 01; 218(4):1250-1264.
Aurora B kinase promotes cytokinesis by inducing centralspindlin oligomers that associate with the plasma membrane. Dev Cell. 2015 Apr 20; 33(2):204-15.
High-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis. Dev Cell. 2014 Jul 28; 30(2):209-23.
Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun. 2012; 3:1072.
Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. Dev Cell. 2007 May; 12(5):713-25.
Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis. Cancer Res. 2007 May 01; 67(9):4113-22.
Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. Mol Cell. 2006 Aug; 23(4):561-74.