"Aurora Kinase B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An aurora kinase that is a component of the chromosomal passenger protein complex and is involved in the regulation of MITOSIS. It mediates proper CHROMOSOME SEGREGATION and contractile ring function during CYTOKINESIS.
Descriptor ID |
D064107
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MeSH Number(s) |
D08.811.913.696.620.682.700.103.750 D12.776.167.049.750
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Concept/Terms |
Aurora Kinase B- Aurora Kinase B
- Serine-Threonine Protein Kinase 12
- Serine Threonine Protein Kinase 12
- Aurora-Related Kinase 2
- Aurora Related Kinase 2
- Aurora B Kinases
- Aurora Kinases B
|
Below are MeSH descriptors whose meaning is more general than "Aurora Kinase B".
Below are MeSH descriptors whose meaning is more specific than "Aurora Kinase B".
This graph shows the total number of publications written about "Aurora Kinase B" by people in this website by year, and whether "Aurora Kinase B" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 0 | 2 | 2 |
2012 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2019 | 0 | 2 | 2 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aurora Kinase B" by people in Profiles.
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Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins. J Mol Biol. 2022 06 30; 434(12):167602.
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Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence. J Cell Sci. 2019 07 01; 132(13).
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Allosteric modulation of a human protein kinase with monobodies. Proc Natl Acad Sci U S A. 2019 07 09; 116(28):13937-13942.
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PLK1 plays dual roles in centralspindlin regulation during cytokinesis. J Cell Biol. 2019 04 01; 218(4):1250-1264.
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Aurora B kinase promotes cytokinesis by inducing centralspindlin oligomers that associate with the plasma membrane. Dev Cell. 2015 Apr 20; 33(2):204-15.
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High-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis. Dev Cell. 2014 Jul 28; 30(2):209-23.
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Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun. 2012; 3:1072.
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Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. Dev Cell. 2007 May; 12(5):713-25.
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Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis. Cancer Res. 2007 May 01; 67(9):4113-22.
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Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. Mol Cell. 2006 Aug; 23(4):561-74.