"Protein Aggregates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any mixture of secondary, tertiary, or quaternary protein molecules which appear as clumps in or outside the cell.
| Descriptor ID |
D066329
|
| MeSH Number(s) |
D05.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Aggregates".
Below are MeSH descriptors whose meaning is more specific than "Protein Aggregates".
This graph shows the total number of publications written about "Protein Aggregates" by people in this website by year, and whether "Protein Aggregates" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 2 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 2 | 2 |
| 2024 | 0 | 3 | 3 |
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Below are the most recent publications written about "Protein Aggregates" by people in Profiles.
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Exploring the rhodanine universe: Design and synthesis of fluorescent rhodanine-based derivatives as anti-fibrillar and anti-oligomer agents against a-synuclein and 2N4R tau. Bioorg Med Chem. 2024 Dec 15; 116:117990.
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Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics. ACS Chem Neurosci. 2024 11 06; 15(21):3915-3931.
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MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity. Proc Natl Acad Sci U S A. 2024 Aug 20; 121(34):e2403392121.
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Chaperones directly and efficiently disperse stress-triggered biomolecular condensates. Mol Cell. 2022 02 17; 82(4):741-755.e11.
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Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease. Nat Commun. 2022 01 10; 13(1):159.
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Nanodroplet Oligomers (NanDOs) of Aß40. Biochemistry. 2021 09 14; 60(36):2691-2703.
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Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aß fibrils. Sci Rep. 2021 01 08; 11(1):247.
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A hydrophobic ratchet entrenches molecular complexes. Nature. 2020 12; 588(7838):503-508.
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Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):19165-19175.
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ß-Amyloid aggregation and heterogeneous nucleation. Protein Sci. 2019 09; 28(9):1567-1581.