"Protein Aggregates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any mixture of secondary, tertiary, or quaternary protein molecules which appear as clumps in or outside the cell.
| Descriptor ID |
D066329
|
| MeSH Number(s) |
D05.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Aggregates".
Below are MeSH descriptors whose meaning is more specific than "Protein Aggregates".
This graph shows the total number of publications written about "Protein Aggregates" by people in this website by year, and whether "Protein Aggregates" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 2 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Aggregates" by people in Profiles.
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Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics. ACS Chem Neurosci. 2024 Nov 06; 15(21):3915-3931.
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Chaperones directly and efficiently disperse stress-triggered biomolecular condensates. Mol Cell. 2022 02 17; 82(4):741-755.e11.
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Nanodroplet Oligomers (NanDOs) of Aß40. Biochemistry. 2021 09 14; 60(36):2691-2703.
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Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aß fibrils. Sci Rep. 2021 01 08; 11(1):247.
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A hydrophobic ratchet entrenches molecular complexes. Nature. 2020 12; 588(7838):503-508.
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Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):19165-19175.
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ß-Amyloid aggregation and heterogeneous nucleation. Protein Sci. 2019 09; 28(9):1567-1581.
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Developing Biologics Tablets: The Effects of Compression on the Structure and Stability of Bovine Serum Albumin and Lysozyme. Mol Pharm. 2019 03 04; 16(3):1119-1131.
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Tuned polymerization of the transcription factor Yan limits off-DNA sequestration to confer context-specific repression. Elife. 2018 11 09; 7.
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Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregates. Cell Death Dis. 2018 03 14; 9(3):407.