 Enhancer Elements, Genetic
"Enhancer Elements, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cis-acting DNA sequences which can increase transcription of genes. Enhancers can usually function in either orientation and at various distances from a promoter.
| Descriptor ID |
D004742
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| MeSH Number(s) |
G02.111.570.080.689.330 G05.360.080.689.330 G05.360.340.024.340.137.750.249
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| Concept/Terms |
Enhancer Elements, Genetic- Enhancer Elements, Genetic
- Element, Genetic Enhancer
- Elements, Genetic Enhancer
- Enhancer Element, Genetic
- Genetic Enhancer Element
- Genetic Enhancer Elements
- Enhancer Elements
- Element, Enhancer
- Elements, Enhancer
- Enhancer Element
- Enhancer Sequences
- Enhancer Sequence
- Sequence, Enhancer
- Sequences, Enhancer
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Below are MeSH descriptors whose meaning is more general than "Enhancer Elements, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Enhancer Elements, Genetic".
This graph shows the total number of publications written about "Enhancer Elements, Genetic" by people in this website by year, and whether "Enhancer Elements, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 1 | 0 | 1 | | 1987 | 2 | 0 | 2 | | 1988 | 1 | 0 | 1 | | 1989 | 2 | 0 | 2 | | 1990 | 1 | 3 | 4 | | 1991 | 1 | 1 | 2 | | 1992 | 2 | 2 | 4 | | 1993 | 4 | 0 | 4 | | 1994 | 0 | 1 | 1 | | 1995 | 1 | 1 | 2 | | 1996 | 2 | 0 | 2 | | 1997 | 0 | 1 | 1 | | 1998 | 2 | 2 | 4 | | 1999 | 0 | 3 | 3 | | 2000 | 1 | 2 | 3 | | 2001 | 1 | 1 | 2 | | 2002 | 2 | 2 | 4 | | 2003 | 3 | 2 | 5 | | 2004 | 0 | 2 | 2 | | 2005 | 1 | 2 | 3 | | 2006 | 2 | 2 | 4 | | 2007 | 1 | 4 | 5 | | 2008 | 1 | 3 | 4 | | 2009 | 0 | 2 | 2 | | 2010 | 3 | 3 | 6 | | 2011 | 4 | 6 | 10 | | 2012 | 5 | 2 | 7 | | 2013 | 11 | 5 | 16 | | 2014 | 8 | 7 | 15 | | 2015 | 5 | 5 | 10 | | 2016 | 6 | 6 | 12 | | 2017 | 6 | 5 | 11 | | 2018 | 2 | 6 | 8 | | 2019 | 2 | 2 | 4 | | 2020 | 5 | 3 | 8 | | 2021 | 4 | 1 | 5 |
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Below are the most recent publications written about "Enhancer Elements, Genetic" by people in Profiles.
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Aneas I, Decker DC, Howard CL, Sobreira DR, Sakabe NJ, Blaine KM, Stein MM, Hrusch CL, Montefiori LE, Tena J, Magnaye KM, Clay SM, Gern JE, Jackson DJ, Altman MC, Naureckas ET, Hogarth DK, White SR, Gomez-Skarmeta JL, Schoetler N, Ober C, Sperling AI, Nóbrega MA. Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region. Nat Commun. 2021 10 21; 12(1):6115.
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Joslin AC, Sobreira DR, Hansen GT, Sakabe NJ, Aneas I, Montefiori LE, Farris KM, Gu J, Lehman DM, Ober C, He X, Nóbrega MA. A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci. Nat Commun. 2021 09 06; 12(1):5253.
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Kasal DN, Liang Z, Hollinger MK, O'Leary CY, Lisicka W, Sperling AI, Bendelac A. A Gata3 enhancer necessary for ILC2 development and function. Proc Natl Acad Sci U S A. 2021 08 10; 118(32).
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Montefiori LE, Bendig S, Gu Z, Chen X, Pölönen P, Ma X, Murison A, Zeng A, Garcia-Prat L, Dickerson K, Iacobucci I, Abdelhamed S, Hiltenbrand R, Mead PE, Mehr CM, Xu B, Cheng Z, Chang TC, Westover T, Ma J, Stengel A, Kimura S, Qu C, Valentine MB, Rashkovan M, Luger S, Litzow MR, Rowe JM, den Boer ML, Wang V, Yin J, Kornblau SM, Hunger SP, Loh ML, Pui CH, Yang W, Crews KR, Roberts KG, Yang JJ, Relling MV, Evans WE, Stock W, Paietta EM, Ferrando AA, Zhang J, Kern W, Haferlach T, Wu G, Dick JE, Klco JM, Haferlach C, Mullighan CG. Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia. Cancer Discov. 2021 11; 11(11):2846-2867.
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Sobreira DR, Joslin AC, Zhang Q, Williamson I, Hansen GT, Farris KM, Sakabe NJ, Sinnott-Armstrong N, Bozek G, Jensen-Cody SO, Flippo KH, Ober C, Bickmore WA, Potthoff M, Chen M, Claussnitzer M, Aneas I, Nóbrega MA. Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5. Science. 2021 06 04; 372(6546):1085-1091.
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Cui XL, Nie J, Ku J, Dougherty U, West-Szymanski DC, Collin F, Ellison CK, Sieh L, Ning Y, Deng Z, Zhao CWT, Bergamaschi A, Pekow J, Wei J, Beadell AV, Zhang Z, Sharma G, Talwar R, Arensdorf P, Karpus J, Goel A, Bissonnette M, Zhang W, Levy S, He C. A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation. Nat Commun. 2020 12 02; 11(1):6161.
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Gacita AM, Dellefave-Castillo L, Page PGT, Barefield DY, Wasserstrom JA, Puckelwartz MJ, Nobrega MA, McNally EM. Altered Enhancer and Promoter Usage Leads to Differential Gene Expression in the Normal and Failed Human Heart. Circ Heart Fail. 2020 10; 13(10):e006926.
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Zhang S, Zhang H, Zhou Y, Qiao M, Zhao S, Kozlova A, Shi J, Sanders AR, Wang G, Luo K, Sengupta S, West S, Qian S, Streit M, Avramopoulos D, Cowan CA, Chen M, Pang ZP, Gejman PV, He X, Duan J. Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants. Science. 2020 07 31; 369(6503):561-565.
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Zraly CB, Zakkar A, Perez JH, Ng J, White KP, Slattery M, Dingwall AK. The Drosophila MLR COMPASS complex is essential for programming cis-regulatory information and maintaining epigenetic memory during development. Nucleic Acids Res. 2020 04 17; 48(7):3476-3495.
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Wu T, Lyu R, You Q, He C. Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ. Nat Methods. 2020 05; 17(5):515-523.
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