 Lipoproteins, HDL
"Lipoproteins, HDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.
| Descriptor ID |
D008075
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| MeSH Number(s) |
D10.532.432 D12.776.521.479
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| Concept/Terms |
Lipoproteins, HDL- Lipoproteins, HDL
- HDL Lipoproteins
- Heavy Lipoproteins
- Lipoproteins, Heavy
- High-Density Lipoproteins
- High Density Lipoproteins
- Lipoproteins, High-Density
- alpha-Lipoproteins
- alpha Lipoproteins
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Below are MeSH descriptors whose meaning is more general than "Lipoproteins, HDL".
Below are MeSH descriptors whose meaning is more specific than "Lipoproteins, HDL".
This graph shows the total number of publications written about "Lipoproteins, HDL" by people in this website by year, and whether "Lipoproteins, HDL" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1980 | 0 | 1 | 1 | | 1981 | 0 | 1 | 1 | | 1982 | 0 | 1 | 1 | | 1984 | 1 | 1 | 2 | | 1985 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1990 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 2 | 1 | 3 | | 1993 | 1 | 0 | 1 | | 1994 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 2 | 0 | 2 | | 1999 | 1 | 2 | 3 | | 2000 | 0 | 1 | 1 | | 2001 | 2 | 1 | 3 | | 2003 | 2 | 2 | 4 | | 2004 | 1 | 1 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 2 | 2 | | 2009 | 1 | 1 | 2 | | 2010 | 3 | 1 | 4 | | 2011 | 1 | 4 | 5 | | 2012 | 2 | 0 | 2 | | 2013 | 2 | 1 | 3 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 3 | 4 | | 2016 | 1 | 1 | 2 | | 2017 | 2 | 1 | 3 | | 2018 | 2 | 0 | 2 | | 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Lipoproteins, HDL" by people in Profiles.
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Le Lay JE, Du Q, Mehta MB, Bhagroo N, Hummer BT, Falloon J, Carlson G, Rosenbaum AI, Jin C, Kimko H, Tsai LF, Novick S, Cook B, Han D, Han CY, Vaisar T, Chait A, Karathanasis SK, Rhodes CJ, Hirshberg B, Damschroder MM, Hsia J, Grimsby JS. Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial. Sci Transl Med. 2021 04 21; 13(590).
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Stackpole KMW, Ollberding NJ, Smith LA, Casson P, Kirk S, Siegel R. Omega-3 Use for the Treatment of Hypertriglyceridemia, Low High-Density Lipoprotein Cholesterol Levels, and Nonalcoholic Fatty Liver Disease in Children with Obesity. Child Obes. 2021 07; 17(5):357-364.
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Harbaum L, Ghataorhe P, Wharton J, Jiménez B, Howard LSG, Gibbs JSR, Nicholson JK, Rhodes CJ, Wilkins MR. Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension. Thorax. 2019 04; 74(4):380-389.
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Huang LH, Zinselmeyer BH, Chang CH, Saunders BT, Elvington A, Baba O, Broekelmann TJ, Qi L, Rueve JS, Swartz MA, Kim BS, Mecham RP, Wiig H, Thomas MJ, Sorci-Thomas MG, Randolph GJ. Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. Cell Metab. 2019 02 05; 29(2):475-487.e7.
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Kailemia MJ, Wei W, Nguyen K, Beals E, Sawrey-Kubicek L, Rhodes C, Zhu C, Sacchi R, Zivkovic AM, Lebrilla CB. Targeted Measurements of O- and N-Glycopeptides Show That Proteins in High Density Lipoprotein Particles Are Enriched with Specific Glycosylation Compared to Plasma. J Proteome Res. 2018 02 02; 17(2):834-845.
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Ganjali S, Momtazi AA, Banach M, Kovanen PT, Stein EA, Sahebkar A. HDL abnormalities in familial hypercholesterolemia: Focus on biological functions. Prog Lipid Res. 2017 07; 67:16-26.
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Sarkar M, Wellons M, Cedars MI, VanWagner L, Gunderson EP, Ajmera V, Torchen L, Siscovick D, Carr JJ, Terry JG, Rinella M, Lewis CE, Terrault N. Testosterone Levels in Pre-Menopausal Women are Associated With Nonalcoholic Fatty Liver Disease in Midlife. Am J Gastroenterol. 2017 05; 112(5):755-762.
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Getz GS, Krishack PA, Reardon CA. Serum amyloid A and atherosclerosis. Curr Opin Lipidol. 2016 10; 27(5):531-5.
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Morton AM, Furtado JD, Lee J, Amerine W, Davidson MH, Sacks FM. The effect of omega-3 carboxylic acids on apolipoprotein CIII-containing lipoproteins in severe hypertriglyceridemia. J Clin Lipidol. 2016 Nov - Dec; 10(6):1442-1451.e4.
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Koren D, Gozal D, Bhattacharjee R, Philby MF, Kheirandish-Gozal L. Impact of Adenotonsillectomy on Insulin Resistance and Lipoprotein Profile in Nonobese and Obese Children. Chest. 2016 Apr; 149(4):999-1010.
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